Textbook of Nephro-Endocrinology

ISBN-13: 9780123738707 / Angielski / Twarda / 2008 / 522 str.

Ajay K. Singh; Gordon H. Williams

Opis

The Textbook of Nephro-Endocrinology is the definitive translational reference in the field of nephro-endocrinology, investigating both the endocrine functions of the kidneys and how the kidney acts as a target for hormones from other organ systems. It offers researchers and clinicians expert, gold-standard analyses of nephro-endocrine research and translation into the treatment of diseases such as anemia, chronic kidney disease (CKD), rickets, osteoporosis, and, hypoparathyroidism.

• Investigates both the endocrine functions of the kidneys and how the kidney acts as a target for hormones from other organ systems
• Presents a uniquely comprehensive and cross-disciplinary look at all aspects of nephro-endocrine disorders in one reference work
• Clear translational presentations by the top endocrinologists and nephrologists in each specific hormone or functional/systems field

Recenzje

"This well-written, relatively concise, and current book will find a home on the shelves of many nephrologists and endocrinologists. Because it is so readable, it should be useful for students, experts, and those in between. I know I will consult my copy on a frequent basis - an unusual event in this era of online material." --N Engl J Med, 2009

"All in all, this is a solid book that provides substantial up-todate information on endocrine aspects of the kidney. I will be glad to pull it down from my shelf rather than one of the true heavyweights to which I would previously have gone for this kind of reading." --Kidney International, 2009

"Written by multidisciplinary experts from several countries, this book is divided into 2 parts and 7 sections. A very useful volume. Each chapter is richly referenced." --Pediatric Endocrinology Reviews

Spis treści

Part 1: The Kidney as an Endocrine Organ Section 1: Erythropoietin 1. Erythropoientin: An Historical Overview of Physiology, Molecular Biology And Gene Regulation 2.Erythropoiesis: The Role of Erythropoietin and Iron 3.Extra-Hematopoietic Action of Erythropoietin 4.Development of Recombinant Erythropoietin and Erythropoietin Analogues 5.Erythropoietin Disease States & Resistance Section 2: Vitamin D, PTH and Novel Regulators of Phosphate 6. Vitamin D and the Kidney: Introduction and Historical Perspective 7.Vitamin D: Molecular Biology and Gene Regulation 8.Molecular Biology of Parathyroid Hormone 9.Endocrine Regulation of Phosphate Homeostasis Section 3: Renin-angiotensin 10.Introduction and Historical Overview 11.Molecular Biology of Renin and Regulation of Its Gene 12. Physiology and Regulation of the RAAS System 13. The Renin Angiotensin Aldosterone System and the Kidney 14. The Renin Angiotensin and the Heart 15. The Renin-Angrotensin blockade: Therapeutic Agents

Part 2: The Kidney as a Hormonal target Section 4: Anti-diuretic Hormone 16. Vasopressin in the Kidney: Historical Aspects 17. Molecular Biology and Gene Regulation 18. Vasopressin Antagonists in Physiology and Disease 19. Diabetes Insipidus and SIADH Section 5: The Atrial Natriuretic Peptides 20. ANP, BNP and CNP Physiology and Pharmacology of the Cardiorenal Axis Section 6: Aldosterone 21.Introduction and Historical Overview 22.Aldosterone Receptors and Their Renal Effects: Molecular Biology and Gene Regulation 23. Aldosterone and Its Cardiovascular Effects 24. Aldosterone Regulation Section 7: Endocrine Disorders in Renal Failure 25. Insulin resistance 26. Growth hormone 27. Sexual Dysfunction in Men and Women with Chronic Kidney Disease 28. Thyroid Status in Chronic Renal Failure Patients 29.Metabolic Acidosis of Chronic Kidney Disease 30.Pregnancy and the Kidney