Synthetic Polymers in Drug and Biotherapeutics Delivery

ISBN-13: 9780323952330 / Angielski / Miękka / 2024

Rangasamy V. Jayakumar; Mar Masson; Deepagan Veerasikku Gopal

Opis

Synthetic Polymers in Drug and Biotherapeutics Delivery covers recent advances in the design, synthesis and application of engineered polymers in the delivery of drugs and other biotherapeutic agents. The book covers new polymers that are fast replacing obsolete polymers in the field of drug delivery. Each chapter focuses on a specific polymer, detailing its design, synthesis, fabrication techniques and applications in drug and biotherapeutics delivery. This thorough examination provides a review of the latest research in this rapidly-changing field. Hence, it will be of interest to materials scientists, pharmaceutical scientists, biomedical engineers, chemical engineers and clinicians with an interest in materials development. Synthetic polymers provide a unique set of opportunities in drug and bio-therapeutic delivery due to their chemical versatility and tunable physicochemical properties. Such polymers can be formulated into nanoparticles, nanofibers, nanogels, microparticles, beads, hydrogels, and scaffolds to suit specific needs such as drug release rate and biodegradation with low toxicity.

Spis treści

1. Role and challenges of synthetic biopolymers in drug/bio-therapeutics delivery 2. Poly (caprolactone) 3. Poly (d,l lactide-co-glycolide) 4. Poly (amidoamines) 5. Poly (vinyl alcohol) 6. Poly (oxozolines) 7. Poly (amides) 8. Poly (ethylenimine) 9. Poly (ethylene oxide) 10. Poly (N-isopropyl acrylamide) 11. Poly (2- hydroxyethyl methacrylate) 12. Poly (N-(2-hydroxypropyl methacrylamide) 13. Poly (dioxanone) 14. Poly (phosphazenes) 15. Blending techniques and formulation strategies 16. Clinical application, regulatory status, and future perspective of synthetic biopolymers in drug/bio-therapeutics delivery