Synthetic Cathinones: Novel Addictive and Stimulatory Psychoactive Substances

ISBN-13: 9783319787060 / Angielski / Twarda / 2018 / 207 str.

Jolanta Zawilska

Spis treści

1.     Introduction – Richard M. Kostrzewa and Trevor Archer

2.     Novel psychoactive substances: classification and general information – Jolanta B. Zawilska and Jakub Wojcieszak (confirmed).

3.     Khat – a natural precursor of synthetic cathinones - Nilesh B. Patel (confirmed)

4.     Analytical techniques for the detection of synthetic cathinones and their metabolites – Piotr Adamowicz and Dariusz Zuba (confirmed).

5.    Metabolism of synthetic cathinones - Kei Zaitsu (confirmed).

6.    Monoamine transporter and receptor interaction profiles of synthetic cathinones: Linda Simmler (confirmed).

7.    Effects of synthetic cathinones on brain neurotransmitters – Krystyna Gołembiowska and Katarzyna Kamińska (confirmed).

8.    Behavioral profile of actions of synthetic cathinones – Scott Rawls (confirmed).

9.    Prevalence and motivation for use of synthetic catinones – Marie-Claire Van Hout (confirmed).

10. The effects and risks associated with synthetic cathinones use in humans – Lauren Karila (confirmed).

11.  Concluding remarks – Jolanta B. Zawilska

O autorze

Jolanta Zawilska is Professor at the Academy of Sciences in Lodz, Poland and Chief of the Chronobiology lab at the Centre for Medical Biology. Dr. Zawilska obtained her PhD in Pharmacology  at the Medical University of Lodz. She has over 35 years of experience in pharmacology/pharmacodynamics and chronobiology. She has written numerous publications and has received awards in recognition of her research.

Blurb

Over the last decade a rapidly increasing number of novel psychoactive substance (NPSs), often marketed as “designer drugs”, “legal highs”, “herbal highs”, “research or intermediate chemicals” and “laboratory reagents”, has appeared on the drug market worldwide in an effort to bypass controlled substance legislation. NPSs encompass a wide range of different compounds and drug classes but had been dominated by synthetic cannabinomimetics and psychostimulatory synthetic cathinones, so-called b-keto amphetamines. Compounds from the later class were first detected in Europe in 2004, and since that time more than 130 new cathinones have been identified and reported to the European Monitoring Centre for Drugs and Drug Addiction. The rapid and extensive worldwide rise of synthetic cathinone abuse is attracting increasing attention, due to many intoxications and overdose deaths.