Synbiotics in Human Health: Biology to Drug Delivery

ISBN-13: 9789819955749 / Angielski

Kamal Dua

Spis treści

Section I: Synbiotics in Disease State

1.      Introduction to Synbiotics
2.      Role of Synbiotics on modulation of inflammation
3.      Role of synbiotics in inflammatory lung diseases
4.      Role of Synbiotics in Neurodegenerative Diseases
5.      Role of Synbiotics in Gastrointestinal Disorders
6.      Role of Synbiotics in Cardiovascular diseases
7.      ROLE OF SYNBIOTICS IN THROMBOTIC DISORDERS
8.      Role of Synbiotics in Reproductive disorders
9.      Role of Synbiotics in Metabolic Disorders
10.   SYNBIOTICS FOR THE PREVENTION AND TREATMENT OF SKIN DISORDERS
11.   Cellular and Molecular mechanisms involving synbiotics in various disease state
12.   Clinical Trial with Synbiotics in Various Disease State
13.   FUTURE PERSPECTIVE AND SAFETY ISSUES OF SYNBIOTICS IN DIFFERENT DISEASES

Section II: Nutraceuticals as Synbiotics

1.      Role of nutraceutical-based synbiotics in the biological homeostasis
2.      Synergistic welfare of synbiotic nutraceuticals on chronic respiratory diseases
3.      Synergistic welfare of symbiotic nutraceuticals on gut health
4.      Synergistic welfare of synbiotic nutraceuticals on neurological function
5.      Synergistic Welfare of Synbiotic Nutraceuticals on Reproductive Health
6.      Quality Control and Evaluation of Synbiotics Neutraceutical Product
7.      Toxicological profile of nutraceutical supplements
8.      TRANSLATIONAL RESEARCH & CLINICAL ADVANCEMENTS WITH NUTRACEUTICAL SUPPLEMENTS
9.      Regulatory Aspects and Bottlenecks for Nutraceuticals
10.   Future prospects and advancement in synbiotics containing Nutraceuticals

Section III: Synbiotics and Drug Delivery

1.      Synbiotics and Drug Delivery: An introduction
2.      Emerging era of “biotics”: Prebiotics, probiotics and synbiotics
3.      Therapeutic potential of synbiotics in management of various disorders
4.      Synbiotics: Safety assessment and role in the prevention of diseases
5.      Synbiotics as a nutraceutical adjuvant: neuroprotective and neurorestorative effects
6.      Synbiotics: Complementary and synergistic approach against different carcinomas
7.      SYNBIOTICS IN ORAL DRUG DELIVERY
8.      Applications of synbiotics as cosmeceuticals
9.      Advanced drug delivery approaches containing synbiotics
10.   Ideal Synbiotics: Pharmacokinetic, pharmacodynamic and safety assessment
11.   Regulatory Aspects of Synbiotics-Based Delivery System
12.   An update on clinical trials on synbiotics

O autorze

Dr. Kamal Dua is a Senior Lecturer in the Discipline of Pharmacy at the Graduate School of Health, University of Technology Sydney (UTS), Australia. He has research experience of over 12 years in the field of drug delivery systems targeting inflammatory diseases. Dr. Dua is also a Node Leader of Drug Delivery Research in the Centre for Inflammation at Centenary Institute/UTS, where the targets identified from the research projects are pursued to develop novel formulations as the first step towards translation into clinics. Dr. Dua researches in two complementary areas; drug delivery and immunology, specifically addressing how these disciplines can advance one another, helping the community to live longer and healthier. This is evidenced by his extensive publication record in reputed journals. Dr. Dua’s research interests focus on harnessing the pharmaceutical potential of modulating critical regulators such as Interleukins and microRNAs and developing new and effective drug delivery formulations for the management of chronic airway diseases. He has published more than 440 research articles in peer-reviewed international journals and authored or co-authored four books. He is an active member of many national and international professional societies.

Blurb

This reference book discusses the role of synbiotics in a wide range of disease states, including cardiovascular, reproductive, metabolic, neurodegenerative, gastrointestinal, thrombotic, skin, and inflammatory disorders. It reviews the functions of probiotics in the diagnosis, prevention, or treatment of various disease states. The book further covers improving the targeting efficiency of synbiotics through advanced drug delivery systems such as nanoparticles, microparticles, liposomes, microemulsion, solid lipid nanoparticles, and nano lipid carriers. The chapter addresses the implications of oral and topical delivery of synbiotics in different diseases and presents the safety assessment of synbiotics and clinical trials associated with synbiotics containing drug delivery systems for the treatment of diseases. The book also explores the synergistic welfare of synbiotics nutraceuticals in various conditions such as chronic respiratory diseases, gut health, and neurological functions and examines the toxicological profile, and regulatory aspects of nutraceutical supplements. As such, this book is a valuable resource for academics, research and industry professionals working in Pharmaceutical Sciences, Food Biotechnology, Immunology, and Health Sciences.​