Supramolecular Structure and Function 9

ISBN-13: 9781402064654 / Angielski / Twarda / 2007 / 318 str.

Greta Pifat-Mrzljak

Opis

The frontiers in scientific research are difficult to define. Nowadays the new knowledge depends not only on new methods and concepts but also on the interaction with other fields of research. Biophysics offers a rational language for discussion among scientists of different disciplines. This is the general philosophy behind the organization of the Summer Schools organized by Rudjer Bo kovi ? Institute, Zagreb, Croatia and the Croatian Biophysical Society from 1981 on each third year. Internationally recognized and successfully established nine international summer schools have been organized under the title -Supramolecular Structure and Function-. The International Summer Schools on Biophysics have a very broad scope devoted to the structure-function relationship of biological macromolecules and to mayor biophysical techniques. The int- tion is to organize courses which provide advanced training at doctoral or postdoctoral level in biosciences. Sixteen main contributions presented here by prominent lecturers illustrate the principals, concepts and methods of b- physics coupled with molecular biology approaches. Since the great diversity of topics the book should be of interest for scientists of different disciplines as was the audience at the School."

Spis treści

Predictions of Protein-Protein Interactions at the Atomic Scale.- An Infrared Study of Fibril Formation in Insulin from Different Sources.- Some Basic Biomolecular NMR for Protein Structure Determination.- Solid State NMR for Studying Membrane Proteins.- Protein Complexes in SUMO Signaling.- Mass Spectrometry and Glycomics.- Mechanisms of Supramolecular Assembly Exemplified by Microtubules and Amyloid Fibril Formation.- Hepatitis B Virus (HBV): The Life-cycle and Assembly of a Complex Virus.- Photo-oxidative Stress in the Presence of a Water-soluble Derivative of C60: ESR and AFM Assays.- Functional EPR Spectroscopy and Imaging of Nitroxides.- Novel Leads for Selective Antibiotics Against Shigellosis by Virtual Screening, Crystallography and Synthesis.- Virtual Ligand Screening: A Method to Discover New Drug Leads.- From Solid State to Bio-Complexity: On the Emerging Science of Emergence.- MR Spectroscopy and the Early Detection of Cancer in Human Subjects.- Microarray and Single Cell Analysis Techniques in Bio-medical Fields.- SOS Hypothesis and the Emergence of Integrative Biology.