Structural Glycobiology

ISBN-13: 9781439854600 / Angielski / Twarda / 2012 / 348 str.

Elizabeth Yuriev; Paul A. Ramsland

Opis

Structural glycobiology is a rapidly growing field of research that examines the structural and functional roles of carbohydrates. This book investigates how research findings have revealed key structural and associated biological information on carbohydrates and glycolipids.

Recenzje

"… beautifully illustrated with fine color illustrations … valuable for a wide audience - from graduate students to established researchers involved in studies of carbohydrates as well as for specialists in the other fields - biochemists, clinical chemists and immunologists."
—Immunological Investigations, 2013

Spis treści

Experimental Techniques to Determine Three-Dimensional Structures: Crystallography and Small-Angle Scattering of Carbohydrate–Protein Complexes and Glycoproteins. Nuclear Magnetic Resonance Studies of Carbohydrate–Protein Interactions. Electron Cryomicroscopy of Large Glycoprotein Assemblies. Theoretical/Modeling Techniques to Predict Three-Dimensional Structures: Protein–Carbohydrate Interactions: Computational Aspects. Docking of Carbohydrates into Protein Binding Sites. Alternative Approaches for Yielding Detailed Structural Information: Mass Spectrometry for Glycomics Analysis of N- and O-Linked Glycoproteins. Glycan-Based Arrays for Determining Specificity of Carbohydrate-Binding Proteins. Carbohydrates in Medicine: Structural Glycobiology: Applications in Cancer Research. Structural Glycobiology: Applications in Organ Transplantation. Structural Glycobiology: Applications in Viral Infection. Developing Drugs from Sugars Current State of Glycosaminoglycan-Derived Therapeutics.

O autorze

Elizabeth Yuriev is with the Monash Institute for Pharmaceutical Sciences at Monash University, Australia. Paul A. Ramsland is with the Centre for Immunology at the Burnet Institute in Melbourne, Australia.