Stimulated Cerebral Blood Flow: Experimental Findings and Clinical Significance

ISBN-13: 9783642771040 / Angielski / Miękka / 2011 / 276 str.

Peter Schmiedek; Karl Einh Upl; Carl-Martin Kirsch

Opis

Das vorliegende Buch enth{lt die Beitr{ge eines internatio- nalen Symposiumszum Thema "Stimulierte Hirndurchblutung." Vorgestellt werden zun{chst neue Erkenntnisse zur Regulation der Hinrdurchblutung. Im 2. Abschnitt kommen verschiedene Methoden zur Messung der Hirndurchblutung zur Sprache, die sowohl unter experimentellen als auch unter klinischen Be- dingungengetestet wurden. Es folgt ein Abschnitt, der ver- schiedene M-glichkeiten zur Stimulation der Hirndurchblutung aufzeigt. Im letzten Abschnitt wird aufdie Bedeutung der stimulierten Hirndurchblutungsmessung zur Bestimmung der ce- rebrovascul{ren Reservekapazit{ten hingewiesen. Dieser Para- meter hat nach den vorliegenden Untersuchungen klinisch- praktische Bedeutung, beispielsweise f}r die Indikations- stellung bei cerebrovascul{ren Eingriffen zur Isch{mie-Pro- phylaxe.

Spis treści

1: Regulation of Cerebral Blood Flow.- Regulation of Cerebral Blood Flow: A Brief Review.- Capillary Perfusion in the Brain.- Intrinsic and Extrinsic Neural Regulation of the Cerebral Circulation.- Endothelium-Dependent Relaxations and Concentrations: Their Physiology in the Cerebral Arteries and Pathology in Experimental Cerebral Vasospasm.- Mechanisms of Cerebral Vasodilatation During Neuronal Activation by Bicuculline: A Review.- Postischemic Hyperperfusion and Outcome: An Experimental Study.- 2: Methods for the Measurement of Cerebral Blood Flow.- Erythrocyte Flow in Cerebral Capillaries Under Resting and Stimulated Conditions.- Continuous Measurement of Acetazolamide Stimulated Cerebral Blood Flow by Laser Doppler Flowmetry.- Transcranial Doppler Ultrasound and Regional Cerebral Blood Flow Assessment of Cerebral Hemodynamics: The Acetazolamide Test.- Continuous Monitoring of Cortical Blood Flow and Intracranial Pressure in Severe Cerebral Trauma.- Role of Cerebral Blood Flow Imaging in the Evaluation of Subarachnoid Hemorrhage and Intracranial Arteriovenous Malformations.- Hemodynamic Assessment of Carotid Artery Obstructive Lesions: Comparison of PET and SPECT.- Cerebral Blood Flow to Cerebral Blood Volume Relationship as a Correlate to Cerebral Perfusion Reserve.- Positron Emission Tomography Activation Studies in Neurological Patients.- 3: Stimulation of Cerebral Blood Flow.- Methods for Manipulation of Regional Brain Perfusion, Intracranial Artery Diameter, and Cerebral Blood Volume.- Carbon Dioxide and Oxygen Reactivity in Cerebral Circulation.- Noninvasive Testing of Vasomotor Reserve.- Identification of Hemodynamic Patients for EC-IC Bypass Surgery.- Effect of Blood Pressure on Cerebral Blood Flow and Infarct Size: Hemodynamic Considerations.- Effects of Acetazolamide on EEG and Intracranial Pressure.- Mental Activity and Changes in Cerebral Blood Flow Evaluated by Transcranial Doppler Sonography.- 4: Clinical Application of Stimulated Cerebral Blood Flow Studies.- Natural History of Patients Defined by Assessment of Cerebral Blood Flow Reserves.- Aspects of Cerebrovascular Autoregulation Following Subarachnoid Haemorrhage.- Doppler CO2 Test in Internal Carotid Artery Occlusions: Prospective and Retrospective Results.- Changes in CBF After Carotid Endarterectomy: Follow-up in Neurologically Asymptomatic Patients.- Effect od Stenosis and Endarterectomy on Internal Carotid Artery Blood Flow.- Cerebrovascular Reserve Capacity Measured with 133-Xenon Dynamic SPECT Before and After Carotid Endarterectomy.- Extra-Intracranial Bypass Surgery in Patients with Hemodynamic Cerebral Ischemia.- Follow-up Studies of Cerebrovascular Reserve Capacity in Patients with Cerebrovascular Disease.