Stem Cells in the Nervous System: Functional and Clinical Implications

ISBN-13: 9783540205586 / Angielski / Twarda / 2004 / 184 str.

Fred H. Gage;Anders Björklund;Alain Prochiantz

Opis

After 40 years of research, scientists have confirmed that persistent neurogenesis occurs in the adult mammalian brain. The obvious next question is: "Are the newly generated neurons functional?" If so, "What are the functions of these new neurons?" This volume intends to clarify both questions by providing the latest data available.

Spis treści

Neurogenesis in Adult Brain: Understanding Its Mechanism and Regulation.- The Logic of Neural Cell Lineage Restriction: Neuropoiesis Revisited.- Astrocytic Nature of Adult Neural Stem Cells in Vivo.- What is the Functional Role of New Neurons in the Adult Dentate Gyrus?- Do Forebrain Neural Stem Cells Have a Role in Mammalian Olfactory Behavior?- Converting ES Cells Into Neurons.- Stem Cell Infidelity.- The Importance of CNS Stem Cells in Development and Disease.- In vivo Properties of In Vitro-Propagated Neural Stem Cells After Transplantation to the Neonatal and Adult Rat Brain.- Neurogenesis in Stroke and Epilepsy.- The Incorrect Use of Transcription Factors: A Key to your (Stem) Cells?- F Leukemia and Leukemic Stem Cells.- Subject Index.