Stem Cell Labeling for Delivery and Tracking Using Noninvasive Imaging

ISBN-13: 9781439807514 / Angielski / Twarda / 2011 / 496 str.

Dara L. Kraitchman;Joseph Wu

Opis

Describes how MR imaging is used to track stem cells as they repair damaged tissue in the body. This book provides a comprehensive overview of cell therapy imaging, ranging from the basic biology of cell therapeutic choices to the preclinical and clinical applications of cell therapy.

Spis treści

Introduction: Stem Cell Types Overview and Rationale for Labeling for Imaging. Human Embryonic Stem Cells. Mesenchymal Stem Cells from Bone Marrow. Hematopoietic Stem Cells. Adipose-Derived Adult Stem Cells. Umbilical Cord Stem Cells. Induced Pluripotent Stem Cells. Radionuclide Approaches to Imaging Stem Cells and Their Biological Effects on the Myocardium. Fluorescence Imaging of Stem Cells In Vivo: Evolving Technologies and Applications. Ultrasound Imaging Basics. MRI Basics and Principles for Cellular Imaging. X-Ray Imaging Basics. Radionuclide Cell-Labeling Methods. Principles of Bioluminescence Imaging and Its Application In Vivo. Quantum Dot Labeling Methods. Magnetic Resonance Imaging Cell-Labeling Methods. Ultrasound Cell-Labeling Methods. X-Ray-Guided Delivery and Tracking of Cells. Multimodality/Fusion Imaging toward Imaging of Structure and Function. Other Non-Stem Cell Therapies for Cellular Tracking—Inflammatory Cell Tracking. Bioluminescence, MRI, and PET Imaging Modalities of Stem Cell-Based Therapy for Neurological Disorders. Clinical Application of Noninvasive Molecular Imaging in Cancer Cell Therapy: The First Reporter Gene-Based Imaging Clinical Trial. Clinical Cardiology Stem Cell Applications. Musculoskeletal Clinical Applications of Stem Cells. Regulatory Hurdles to Translation. Index.