Part1. Microvesicles.- Chapter1. Stem cell-derived microvesicles for regenerative medicine: A new paradigm for cell-based-cell-free therapy.- Chapter2. Secretome: Pharmaceuticals for Cell Free Regenerative Therapy.- Chapter3. Microvesicles preparation from mesenchymal stem cells.- Chapter4. Exosomes for repair, regeneration and rejuvenation.- Chapter5. Pro-inflammatory cytokines significantly stimulate extracellular vesicle production by adipose-derived and umbilical cord-derived mesenchymal stem cells.- Part2. Stem cells.- Chapter6. An evolution of stem cell products in medicine: a future of off-the-shelf products.- Chapter7. Off-the-shelf mesenchymal stem cell technology.- Chapter8. Ethical and legal issues of cord blood stem cell banking.
Phuc Van Pham received his Ph.D. in Human Physiology from Vietnam National University, Ho Chi Minh City, Vietnam. He is currently a Professor of Biology at Vietnam National University and Acting Director of the Laboratory of Stem Cell Research and Application. He is a longstanding lecturer and translational scientist at the University, and is a member of several societies and journal editorial boards focused on stem cells.
Dr. Pham and his colleagues have established one of the first multidisciplinary stem cell centers in Vietnam, and he has successfully launched an array of technologies in stem cell isolations. His research interests include stem cell isolation, stem cell therapy, mesenchymal stem cells, cancer stem cells, immunotherapy and regenerative medicine and he has published extensively in these areas.
After many years of experience as an embryologist, cell biologist, and molecular biologist, collaborating with leading researchers in Singapore, Japan, and the United States, Dr. Pham is a student again, keen to reach beyond the traditional boundaries of biology.
This invaluable resource discusses the current revolution in stem cell-based drugs and their potential use in clinical applications. Each chapter is contributed by a pre-eminent scientist in the field. An introductory section presents current stem cell drugs and stem cell-based products and a discussion of production, quality control, mechanisms, and efficacy. Following sections include discussions on stem cell-derived microvesicles based products, and derived exosomes based products.
Stem Cell Drugs - A New Generation of Biopharmaceuticals and the other books in the Stem Cells in Clinical Applications series are invaluable to scientists, researchers, advanced students and clinicians working in stem cells, regenerative medicine or tissue engineering. This groundbreaking volume is also essential reading for those researching or studying drug development or pharmaceutical science.