Stem Cell Anthology: From Stem Cell Biology, Tissue Engineering, Cloning, Regenerative Medicine and Biology

ISBN-13: 9780123756824 / Angielski / Twarda / 2009 / 402 str.

Robert Lanza

Opis

The fields of stem cell research, regenerative medicine, tissue engineering, and cloning are very closely related. It is important for researchers in each of these disciplines to be aware of the methods and principles in the others. Elsevier publishes some of the highest individual references in these areas. Bringing together the principles, applications, and basic understanding in these related areas of science will provide a new reference which is serve the needs of a variety of researchers. Edited by Dr. Bruce Carlson, Stem Cell Anthology will be valuable to researchers and students who need to save time and link concepts to principles, applications, and methods in order to work more effectively and see links for potential collaborations.

• Includes a collection of chapters by leaders in the stem cell field including the first researchers to discover iPS cells and multiple Nobel Laureates
• Provides the most detailed introduction to basic properties of major embryonic and adult stem cells by highlighting breakthrough discoveries in the nervous system, spinal cord, heart, pancreas, epidermis, musculo-skeletal, retina - leading areas of stem cell research in human application
• Details technical laboratory set up for practitioners, technicians, and administrators

Spis treści

I. Introductory Chapters
Pluripotential stem cells from vertebrate embryos: Present perspective and future challenges
Postnatal stem cells
Adult epithelial tissue stem cells
Mesenchymal stem cells
Stem cells, plasticity and regeneration

II. Methods for Preparing Embryonic or Pluripotent Stem Cells
Setting up a facility for human embryonic stem cell research
Approaches for derivation and maintenance of human embryonic stem cells: Detailed procedures and alternatives
Derivation and differentiation of human embryonic germ cells
Genetic manipulation of human embryonic stem cells
Induced pluripotential stem cell derivation

III. Types and Properties of Stem Cells
Molecular basis of pluripotency
Characteristics and characterization of human pluripotential stem cells
Multipotent adult progenitor cells
Bone marrow stem cells: Properties and pluripotency
Hematopoietic stem cell properties, markers, and therapeutics
Stem cells in the gastrointestinal tract
Stem cells derived from amniotic fluid and placenta
Nuclear transfer for stem cells

IV. Application of Stem Cell Biology to Regenerative Medicine
Neural stem cells for central nervous system repair
Spinal cord injury
Stem cells and heart disease
Cell-based repair for cardiovascular regeneration: What, why, how and where are we going in the next 5-10 years
Pancreatic stem cells
Insulin-producing cells derived from stem cells: A potential treatment for diabetes
Regeneration of epidermis from adult keratinocyte stem cells
Implantation of myogenic cells in skeletal muscles
Cell-based therapies for musculoskeletal repair
Retinal pigment epithelium derived from embryonic stem cells

O autorze

Bruce M. Carlson, MD, PhD, is Professor Emeritus of Anatomy in the Department of Cell and Developmental Biology in the University of Michigan Medical School in Ann Arbor. He served as chair of that department from 1998-2000. He is also Research Professor Emeritus in the school's Institute of Gerontology, of which he was the director from 2000 to 2003. Professor Carlson writes the majority of the book himself but he has suggested that he may bring in one or two contributors this time round to cover areas that he is not as up to date on as he once was. We have spoken about bringing in a co-author and he is open for this to happen for the 7th edition when he has had time to find someone suitable.