Spinal Afferent Processing

ISBN-13: 9781468449969 / Angielski / Miękka / 2013 / 550 str.

Opis

Some 29 scientists from the fields of neuroanatomy, neurochemistry, neu- rophysiology, neuropharmacology, and behavior have contributed their ef- forts to this testimonial on behalf of the contributions made by Dr. F. W. L. Kerr to science and to those with whom he interacted. The intention of the contributors to this volume was to deal with the manifold advances that pertain to the substrates in spinal cord relating to the processing of sensory infor- mation, a subject that in one form or another provoked time and again Kerr's native enthusiasm for research. The organization of the book follows a natural course from the peripheral innervation of the somatic and visceral organs (Winkelmann, Chapter 2) to the effective stimuli that activate these fibers and give rise to sensation under normal and pathological conditions (Campbell and Meyer, Chapter 3; Dubner and colleagues, Chapter 13; Dyck, Chapter 14) to the course these afferent systems take to enter the spinal cord (Coggeshall, Chapter 4) and to the organization of the systems through which this afferent information reaches the brain (Willis, Chapter 11; Vierck and colleagues, Chapter 12).

Spis treści

1 A Short Biography of F. W. L. Kerr, M.D..- 2 Sensory Receptors of the Skin.- 3 Primary Afferents and Hyperalgesia.- 4 Nonclassical Features of Dorsal Root Ganglion Cell Organization.- 5 Organization of Dorsal Horn Neurotransmitter Systems.- 6 Neurotransmitter Receptor Sites in the Spinal Cord.- 7 The Pattern and Place of Nociceptive Modulation in the Dorsal Horn: A Discussion of the Anatomically Characterized Neural Circuitry of Enkephalin, Serotonin, and Substance P.- 8 The Central Pharmacology of Primary Afferents with Emphasis on the Disposition and Role of Primary Afferent Substance P.- 9 Dorsal Horn Neurons and Their Sensory Inputs.- 10 Spinal Substrates of Visceral Pain.- 11 Ascending Somatosensory Systems.- 12 The Spinal Pathways Contributing to the Ascending Conduction and the Descending Modulation of Pain Sensations and Reactions.- 13 Sensory-Discriminative Capacities of Nociceptive Pathways and Their Modulation by behavior.- 14 Detection Thresholds of Cutaneous Sensations in Health and Disease in Man.- 15 Control Systems for Nociceptive Afferent Processing: The Descending Inhibitory Pathways.- 16 Modulatory Effects of Descending Systems on Spinal Dorsal Horn Neurons.- 17 The Controversial Nature of the Evidence for Neuroplasticity of Afferent Axons in the Spinal Cord.- 18 The Question of How the Dorsal Horn Encodes Sensory Information.- 19 Aspects of Sensory Processing through Convergent Neurons.- 20 The Effects of Intrathecally Administered Opioid and Adrenergic Agents on Spinal function.