Sperm Chromatin for the Clinician: A Practical Guide

ISBN-13: 9781461478423 / Angielski / Miękka / 2013 / 314 str.

Armand Zini; Ashok Agarwal

Opis

This concise, truncated version of Zini and Agarwal's Sperm Chromatin: Biological and Clinical Applications in Male Infertility and Assisted Reproduction offers select, clinical chapters for a handy, more affordable, state-of-the-art resource. Sperm Chromatin for the Clinician addresses such vital issues as: -Male subfertility and sperm chromatin damage -Aging and sperm DNA damage -Cancer and implications for sperm quality -Environmental factors -Cryopreservation and sperm DNA integrity -Postnatal effects of sperm chromatin damage Practical for clinicians and researchers alike, Sperm Chromatin for the Clinician contains all of the need-to-know information about this cutting-edge topic in reproductive medicine.​

Spis treści

Part I: Biological Determinants of Sperm Chromatin Damage.- Sperm Chromatin: An Overview.- Spermatogenesis: An Overview.- Role of Oxidative Stress in the Etiology of Sperm DNA Damage.- Abortive Apoptosis and Sperm Chromatic Damage.- Spermiogenesis in Sperm Genetic Integrity.- Part II: Clinical Aspects of Sperm Chromatin Damage.- Male Subfertility and Sperm Chromatin Damage.- Aging and Sperm DNA.- Cancer in Males: Implications for Sperm Quality, Fertility, and Progeny Outcome.- Sperm Chromatin and Environmental Factors.- Effects of Male Accessory Gland Infection on Sperm Parameters.- Antioxidants and Sperm DNA Damage.- Part III: Sperm Chromatin and Assisted Reproductive Technologies (ART).- The Impact of Sperm Processing and Cryopreservation on Sperm DNA Integrity.- Sperm Chromatin and ART (IUI, IVF and ICSI).- Sperm DNA Damage and Pregnancy Loss after IVF and ICSI.- Postnatal Effects of Sperm Chromatin Damage.- Evaluation of Chromatin and DNA Integrity in Testicular Sperm.- Clinical Utility of Sperm DNA Integrity Tests.

O autorze

Armand Zini, MD, Department of Surgery, Division of Urology, McGill University, St. Mary's Hospital Center, Montreal, QC, Canada 

Ashok Agarwal, PhD, HCLD (ABB), Center for Reproductive Medicine, Glickman Urological and Kidney Institute, Cleveland Clinic, Cleveland, OH, USA