1. Introduction: Smart and Intelligent Nanomaterials for Biosensors 2. Physicochemical Properties of Smart and Intelligent Nanomaterials for Biosensors 3. Classifications and Functionalization of Smart and Intelligent Nanomaterials for Biosensors 4. Synthesis and Characterization of Smart and Intelligent Nanomaterials for Biosensors 5. MXenes and its Hybrid Composites for Fabricating Biosensors 6. Carbon and its Hybrid Composites for Fabricating Biosensors 7. Therapeutic Applications of Biosensors Fabricated from Smart and Intelligent Nanomaterials 8. Recent Advances in Smart Biosensing Technology for Medical Diagnoses 9. Nanomaterials-based Biosensors for Environmental Applications 10. Nanomaterials-based Biosensors for Agricultural Applications 11. Microfluidics/Nanofluidics-based Smart Approaches for Biosensing Applications 12. Nanomaterials-based Biosensors for Food and Feed Applications 13. Market Trends of Smart and Intelligent Nanomaterials-based Biosensors 14. Challenges, Significance and Prospects in Next Generation Nanomaterials-Based Biosensor Technology