Skin and Arthropod Vectors

ISBN-13: 9780128114360 / Angielski / Miękka / 2018 / 516 str.

Opis

Skin and Arthropod Vectors discusses immunity during the transmission of arthropod-borne diseases. Recent research on skin immunity and the skin microbiome reveals the complexity of the skin and its importance in the development of immunity against arthropod-borne diseases. In such diseases, the skin interface has been shown as an essential site for pathogens to hide from the immune system (such as with malaria, borrelia, leishmania, trypanosome, etc.). and as a potential site of persistence. This work helps researchers develop more efficient diagnostic tools and vaccines, and gives scientists and students a better understanding of why humans and animals are attractive to arthropods.

• Offers the only compilation of research focusing on both the skin interface and arthropod vectors, with contributions from international experts
• Advances research in the effort toward generating more effective diagnostic tools and vaccines
• Serves as supplemental material for dermatology lectures or specialized lectures on medical entomology and skin immunity

Spis treści

1. Skin Immunity and Microbiome Nathalie Boulanger and Cédric Lenormand 2. Arthropods: Definition and Medical Importance Gérard Duvallet, Nathalie Boulanger and Vincent Robert 3. Impact of Skin Microbiome on Attractiveness to Arthropod Vectors and Pathogen Transmission Niels O. Verhulst, Nathalie Boulanger and Jeroen Spitzen 4. Arthropod Saliva and Its Role in Pathogen Transmission: Insect Saliva Mosquito Saliva, Skin, Allergy, and the Outcome of Malaria Infection-From Mice to Men Claudia Demarta-Gatsi, Salaheddine Mécheri and Richard E. Paul Role of Sand Fly Saliva on Leishmania Infection and the Potential of Vector Salivary Proteins as Vaccines Shadden Kamhawi, Jesus G. Valenzuela, Iliano V. Coutinho-Abreu, Cláudia Ida Brodskyn 5. Tick Saliva and Its Role in Pathogen Transmission Sarah Bonnet, Mária Kazimírová, Jennifer Richardson and Ladislav Simo 6. Insect-Borne Pathogens and Skin Interface: Flagellate Parasites and Skin Interface Leishmaniasis Natalia Tavares, Léa Castellucci, Camila de Oliveira, Cláudia Brodskyn 7. Trypanosomiasis Dorien Mabille, Louis Maes, Guy Caljon 8. Skin and Other Pathogens: Malaria and Plague Emergence of a Skin Phase in Mammalian Malaria Pauline Formaglio, Laura Mac-Daniel, Rogerio Amino, Robert Ménard Yersinia Pestis and Plague Jeffrey G. Shannon 9. Insect-Borne Viruses and Host Skin Interface Christopher G. Mueller and Van-Mai Cao-Lormeau 10. Tick-Borne Bacteria and Host Skin Interface Quentin Bernard, Ema Helezen and Nathalie Boulanger 11. Tick-Borne Viruses and Host Skin Interface Mária Kazimírová, Pavlína Bartíková and Iveta Stibrániová 12. Skin and Arthropod-Borne Diseases: Applications to Vaccine and Diagnosis Live Vaccines Against Preerythrocytic Malaria: A Skin Issue? Laura Mac-Daniel, Rogerio Amino, Robert Ménard Lyme Vaccine: Borrelia and Tick as Targets to Identify Vaccine Candidates Against Lyme Borreliosis? Ema Helezen, Nathalie Boulanger 13. Tools to Decipher Vector-Borne Pathogen and Host Interactions in the Skin Pauline Formaglio, Joppe W. Hovius, Chetan Aditya, Joana Tavares, Lauren M.K. Mason, Robert Ménard, Nathalie Boulanger and Rogerio Amino

O autorze

Dr. Nathalie Boulanger has been associate professor in parasitology at the University of Strasbourg, France, since 1995. For more than a decade, her research team has developed a project on skin and Lyme borreliosis. The research developed covers the main aspects of the interaction of arthropod vectors and the skin: role of arthropod saliva, skin microbiome, development of in vitro and in vivo models, applications of the topics to diagnostics and vaccine aspects, and more. Dr. Boulanger has received both Fulbright and Monahan grants and has past experience researching malaria and coccidiosis vaccines. She has teaching experience in zoology, public health, entomology, parasitology, and medical mycology.