1. Skill-mix for primary and chronic care: definitions, conceptual framework and relevance for policy and practice Claudia B. Maier, Gemma A. Williams, Hannah Budde, Laura Pfirter, Reinhard Busse and Matthias Wismar; 2. Skill-mix changes: what evidence on patent outcomes and health systems? Claudia B. Maier, Hannah Budde, Laura Pfirter, and Marieke Kroezen; 3. Implementing skill-mix changes: lessons for policy and practice Claudia B. Maier, Giada Scarpetti, Marieke Kroezen, Mathilde S. Akeroyd, Hannah Budde, Laura Pfirter, and Matthias Wismar; 4. Keeping people healthy: skill-mix innovations for improved disease prevention and health promotion Stephan van den Broucke, Katarzyna Czabanowska; Hannah Budde, Laura Pfirter, and Claudia B. Maier; 5. Caring for people with acute conditions: transitional care, relocation of care and new division of work Ivy Bourgeault, Christine Bond, Romy Mahrer-Imhof, Hannah Budde, Bernd Rechel, and Claudia B. Maier; 6. Chronic conditions and multimorbidity: skill-mix innovations for enhanced quality and coordination of care Juliane Winkelmann, Gemma A. Williams, Mieke Rijken, and Katherine Polin; 7 Long-term and palliative care at home: skill-mix innovatons for enhanced responsiveness and satisfaction of patients and caregivers Elke Berger, Ramona Backhaus, Jans Hamers, Peter Pype, Pauline Boeckxstaens, Laura Pfirter, and Claudia B. Maier; 8. Addressing the particular challenges of patients living in rural and remote areas and for disadvantaged groups: skill-mix innovations to improve access and quality of care Jan de Maeseneer, Giada Scarpetti, Hannah Budde, and Claudia B. Maier; 9. Education and planning: anticipating and responding to skill gaps, changing skill needs and competencies Ronald Batenburg and Marieke Kroezen; 10. Implementing skill-mix innovations: role of policy and financing Giada Scarpetti, Claudia B. Maier, Hannah Budde, Dheepa Rajan, Erica Richardson, and Walter Sermeus; 11. Change management in health care settings: organizational strategies to foster skill-mix changes Marieke Kroezen, Ellen Kuhlmann, Christian Gericke, and Gilles Dussault.