Single-Cell Omics: Volume 1: Technological Advances and Applications

ISBN-13: 9780128149195 / Angielski / Miękka / 2019 / 490 str.

Debmalya Barh; Vasco Azevedo

Spis treści

Section I Overview of Single-Cell Omics1. Single-Cell Omics: An Overview2. Recent Progress in Single-Cell Sequencing3. Cellular Heterogeneity and Single-Cell Omics4. Single-Cell Omics: Cellular Functions5. Single-Cell Omics: Deciphering Tumor Clonal Architecture

Section II Omics Technologies in Single-Cell6. An Overview of Single-Cell Isolation Techniques7. Microfluidic Techniques for Single-Cell Culture8. Single-Cell Omics in Noninvasive Diagnosis and Testing-Surface-Enhanced Raman Spectroscopy-Based Approach9. Single-Cell Genomics: Technology and Applications10. Single-Cell Metagenomics11. Single-Cell Epigenomics: Technology and Applications12. Single-Cell Transcriptomics: Technology and Applications13. Single-Cell Transcriptomics and Proteomics of Skeletal Muscle: Technology and Applications14. Single-Cell Proteomics: Technology and Applications15. Single-Cell Metabolomics: Technology and Applications16. Single-Cell Phenomics in Budding Yeast: Technologies and Applications17. Robotics in Single-Cell Omics18. Single-Cell Editing: The CRISPR/Cas9 and Applications

Section III Data Analysis in Single-Cell Omics19. Data Analysis in Single-Cell RNA-Seq20. Systems-Level Understanding of Single-Cell Omics

O autorze

Dr. Debmalya Barh is the Founder and Principal Scientist of Institute of Integrative Omics and Applied Biotechnology (IIOAB), INDIA. He is having 15+ years leading academic, healthcare, molecular diagnostic, and bioinformatics industry experience and an expert in integrative omics-based biomarkers, targets and targeted drug discovery, and personalized medicine in cancers and various complex diseases. He works with more than 400 scientists from 100+ top ranked organizations across 40+ countries and has 220+ publications and a branded editor for 10+ cutting-edge omics related reference books. He is a reviewer of journals from Nature publications, Elsevier and AACR Journals, CMAJ, NAR, Molecular Medicine, Gene Therapy, BMC Series, Bioinformatics, PLOS etc. Due to his significant contribution in the field; he has been recognized by Who's Who in the World and Limca Book of Records. Dr. Vasco Azevedo is a full professor at the Department of Genetics, Ecology, and Evolution, Institute of Biological Sciences, Federal University of Minas Gerais, Brazil. He is a CNPq (Conselho Nacional de Desenvolvimento Científico e Tecnológico) researcher 1A, member of the Brazilian Academy of Sciences, Commander of the Order of Scientific Merit of the MCTI of the genetics advisory committee and the public policy working group on biotechnology and genetic resources of COBRG/CNPq, coordinator of the Associated International Laboratory Bactinfl from INRAE and UFMG, and vice-president of the Brazilian Association of Bioinformatics and Computational Biology. He holds a degree in veterinary medicine from the School of Veterinary Medicine of the Federal University of Bahia (1986), a master's degree (1989), a doctorate (1993) in the genetics of microorganisms from the Institut National Agronomique Paris Grignon, and a doctorate in bioinformatics from UFMG (2017). He did his postdoctorate work with the Department of Microbiology, School of Medicine, University of Pennsylvania, United States (1994). He was a professor at the Institute of Biomedical Sciences of the University of São Paulo (2004). He is an expert in genetics and bioinformatics and his work mainly focuses on genomics, transcriptomics, proteomics, metabolomics, vaccine development, diagnostics, and the development of next generation probiotics. He has more than 600 scientific publications, 14 books, and 60 chapters as well as 12 patents.