Silkworm Biofactory: Silk to Biology

ISBN-13: 9780367780722 / Angielski / Miękka / 2021 / 300 str.

Katsumi Maenaka; Enoch Y. Park

Opis

This book provides a comprehensive and up to date review about recent and future trends of silkworm biotechnology and potential pharmaceutical applications. Today’s biotechnology-based industry faces hurdles in advancement owing to the lack of proper gene expression systems. There are still many proteins for which gene structure are unknown

Spis treści

BIO PRODUCTS FROM SILKWORMS. Basic and Applied Genetics of Silkworms. Silkworm Breeding. Focus on Physiological Vital Proteins from Silkworm, Bombyx mori. Metabolism of Molting Hormone and Juvenile Hormone in Silkworm. Post-translational Modification in Silkworm. BIO PRODUCTS FROM SILKWORMS. Glycoprotein biosynthesis of silkworm. BacMam System in Silkworm. Transgenic Silkworm. Glycosyltransferase Expression in Silkworm and Its Applications in Glycobiology. Bio products from silkworms. Silkworm Expression of Cell Surface Molecules. Expression and Purification of Mitochondrial Membrane Protein OPA1 for Reconstitution of Membrane Fusion. Virus-like Particles Expression in Silkworms. Gene Delivery Based on Bombyx mori Nucleopoplyhedrovirus (BmNPV). Development of New Biomaterials from Insect and its Virus. Production of Medical and Cosmetic Products Using Transgenic Silkworms. Comparative Investigation of Influenza Virus-like Particles from Synthetic Chemical Substance and Silkworm. BIO PRODUCTS FROM SILKWORMS. Bio products from silkworms.

O autorze

Prof. Enoch Y. Park is a professor at Research Institute of Green Science and Technology (RIGST), Shizuoka, Japan. He received a Ph.D. in 1990 from the University of Tokyo. He was assistant professor at Nagoya University, Japan from 1990 and then associate professor at Shizuoka University from 1994 and a professor from 1999. In 2013 he was appointed Director of RIGST, Shizuoka University. He developed a bacmid expression system in silkworm. He has authored/co-authored about 280 original articles, reviews and book chapters, in the field of protein expression, biotechnology, and nanobiotechnology.

Prof. Katsumi Maenaka is a professor at Laboratory of Biomolecular Science, and Director, Center for Research and Education on Drug Discovery, Faculty of Pharmaceutical Sciences, Hokkaido University, Japan. He received his Ph.D. in 1996 from the University of Tokyo. He was a HFSP postdoctoral fellow at University of Oxford, assistant professor at National Institute of Genetics, associate professor at Kyushu University and professor at Hokkaido University in 2010. He developed a bacmid expression system in silkworm with Prof. Park. He has published many original articles, reviews and book chapters, in the field of protein engineering, structural biology, immunology, virology and drug discovery.