Signal Transduction in Testicular Cells: Basic and Clinical Aspects

ISBN-13: 9783662032329 / Angielski / Miękka / 2012 / 354 str.

V. Hansson;F.O. Levy;K. Tasken

Opis

The European Workshop on Molecular and Cellular Endocrinology of the Testis was organized for the first time at Geilo, Norway, 8-11 April 1980. Since then, these meetings have been held in Holland, France, Italy, England, Sweden/Finland (Aland), Germany, and Bel gium. This year the circle has been closed: The 9th European Testis Workshop is back in the Norwegian mountains where it all started. The Scientific Committee of the First European Testis Workshop included Dr. H.J. van der Molen (Rotterdam), Dr. V. Hansson (Oslo), Dr. B. Cooke (London), Dr. V. Monesi (Rome), Dr. E.M. Ritzen (Stockholm), and Dr. J.M. Saez (Paris). Since then, two of the founders have left the Scientific Committee. Dr. Monesi died suddenly on 29 December 1979, 3 1/2 months before the first workshop took place. Thus, in spite of being one of the founders, he never experienced a Eu ropean Testis Workshop. Dr. Mario Stefanini, from the same research institute in Rome, replaced Dr. Monesi on the Scientific Committee. Another founder of this workshop series, Dr. H.J. van der Molen (Rot terdam), is one of the pioneers in research on molecular endocrinology of the testis in Europe. He left the Scientific Committee due to a change in his scientific career and was replaced by Dr. F.F.G. Rom merts, whose lectures on "Testomania" have been a characteristic fea ture of these meetings."

Spis treści

1 The Roles of the Cell-Selective Nuclear Receptor SF-1 in Reproductive Function.- 2 Regulation of Steroid Hormone Production.- 3 A Role for cAMP-Response Element Motifs in Transcriptional Regulation of Postmeiotic Male Germ Cell-Specific Genes.- 4 Cyclic Nucleotide-Gated Channels in Sperm.- 5 CREM: A Transcriptional Master Switch Governing the cAMP Response in the Testis.- 6 Targeted Disruption of the Protein Kinase A System in Mice.- 7 Posttranscriptional Regulation of Postmeiotic Gene Expression.- 8 Isolation and Culture of Immature Rat Type A Spermatogonial Stem Cells.- 9 Androgen Receptor in Transcriptional Regulation.- 10 The 3?-Hydroxysteroid Dehydrogenase/Isomerase Gene Family: Lessons from Type II 3?-HSD Congenital Deficiency.- 11 The Src Family of Protein Tyrosine Kinases.- 12 Sperm-Zona Pellucida Interaction: A Model for Zona Receptor Kinase-Mediated Signaling.- 13 The Use of Spermatids for Human Conception.- 14 Evidence-Based Andrology: The Importance of Controlled Clinical Trials.- 15 Molecular Genetics and Neurobiology of Kallmann’s Syndrome.- 16 The Polymorphisms of Gonadotropin Action: Molecular Basis and Clinical Implications.- Previous Volumes Published in this Series.