Sexually Transmitted Infections: Advances in Understanding and Management

ISBN-13: 9783030021993 / Angielski / Twarda / 2020 / 427 str.

Cristaudo, Antonio

Opis

This comprehensive, well-illustrated, and easily accessible book documents the latest research outcomes concerning sexually transmitted infections (STIs) and describes important advances in their diagnosis and treatment. The changes in the epidemiology and clinical aspects of STIs that have occurred over the past decade are fully explored, with special attention to core groups and patients with immunological disorders. The emerging challenges associated with particular sexually transmitted pathogens, including C. trachomatis, N. gonorrhoeae, HPV, and HIV, are identified and discussed. Readers will find detailed information on modern preventive strategies, new laboratory and diagnostic techniques, and a range of innovative treatments, including vaccines, continuous antiretroviral therapy, and drugs against hepatitis viruses. Attention is also drawn to new directions in biomedical research that promise clinical benefits. The combination of a detailed clinical and research approach, with emphasis on new knowledge and innovative aspects, ensures that the book will be of value to a wide readership comprising both clinicians and researchers.

Spis treści

Preface.- Section 1 Global Epidemiology.- Global epidemiology of Sexually Transmitted Infections in the 21st century: beyond the numbers.- The new epidemiology of Human Immunodeficiency Virus infection.- Social and Behavioral determinats of STI in the 21st century. An overview.- Section 2 Prevention and control of STI.- Behavioral Prevention Strategies for STI.- Vaccines for STIs: present and future directions.- Section 3 Laboratory and diagnostic techniques.- New diagnostic approaches to viral Sexually Transmitted infections .- New tools for the diagnosis of bacterial STIs.- Section 4 The clinical spectrum of STI.- The syphilis after the year 2000.- Neisseria gonorrhoeae infections.- Novel approach to Chlamydia trachomatis Infections in female and male.- Genital Herpes: clinical and scientific novelties.- Clinical Management of anogenital warts and Intraephitelial neoplasia.- Sexually Transmitted Hepatitis.- Bacterial Vaginitis and Vaginosis .- The clinical spectrum of Human Immunodeficiency Virus infection.- Donovanosis, chancroid and endemic treponematoses. Clinical features and control.- The Lymphogranuloma venereum as re-emerged sexually transmitted infection .- HHV-8 Infection and Kaposi Sarcoma .- Section 5 Modern challenges in STI area.- Biological pathways of HPV-induced carcinogenesis .- Antimicrobial resistance of Neisseria Gonorrhoeae: a new challenge.- The men who have sex with men (MSM) as core group for STI .- The vaccines against HPV: a new direction for STI prevention.- Immunological strategies against T. Pallidum infections.- Natural history of anal HPV Infection.

O autorze

Antonio Cristaudo is  Head of the STI/HIV Department at the San Gallicano Dermatological Institute, a historic health and research institute in Rome, Italy. He has vast expertise  in the management of patients with or at-risk for STIs. He began his clinical and research activity at the San Gallicano Dermatologic Institute in 1987.  He has been the principal investigator on various trials and scientific projects on STIs and HIV and HPV infections. He is the author of more than 180 scientific articles in indexed journals, most of them in the field of STIs and of dermatological diseases. He is past-President of the Italian Association of Hospital Dermatologists (ADOI).      

Massimo Giuliani is a behavioral scientist and an epidemiologist with expertise in the epidemiology, prevention, and control of STIs and HIV infection. From 1990 to 2009 he was scientific coordinator of the Italian Sentinel Surveillance for STIs at the Italian Institute of Health , Rome, Italy. Since 1995 he  is clinical psychologist and researcher at the STI Unit of the San Gallicano Dermatological Institute in Rome, Italy where he is still involved in clinical practice with STI and HIV patients, and coordinating or acting as principal investigator for behavioral prevention programs, trials, and scientific projects on STIs,  HIVand HPV infections. Dr. Giuliani is the author of over 200 scientific articles in the field of STIs and HIV infection. He is a reviewer for various leading biomedical journals and is also a member of the Scientific Committee of the Italian Multidisciplinary Society for STIs (SIMAST). 

Blurb

This comprehensive, well-illustrated, and easily accessible book documents the latest research outcomes concerning sexually transmitted infections (STIs) and describes important advances in their prevention, diagnosis and treatment. The changes in the epidemiology and clinical aspects of STIs that have occurred over the past decade are fully explored, with special attention to core groups and patients with immunological disorders. The emerging challenges associated with particular sexually transmitted pathogens, including C. trachomatis, N. gonorrhoeae, HPV, and HIV, are identified and discussed. Readers will find detailed information on modern preventive strategies, new laboratory and diagnostic techniques, and a range of innovative treatments, including vaccines, continuous antiretroviral therapy, and new drugs against hepatitis viruses. Attention is also drawn to new directions in biomedical research that promise clinical benefits for the patients and communities. The combination of a detailed clinical and research approach, with emphasis on new knowledge and innovative aspects, ensures that the book will be of value to a wide readership comprising both clinicians and researchers.