Sedimentation Velocity Analytical Ultracentrifugation: Discrete Species and Size-Distributions of Macromolecules and Particles

ISBN-13: 9780367878283 / Angielski / Miękka / 2019 / 244 str.

Peter Schuck

Opis

A follow-up to the experimental and instrumental aspects described in Basic Principles of Analytical Ultracentrifugation, the volume Sedimentation Velocity Analytical Ultracentrifugation: Discrete Species and Size-Distributions of Macromolecules and Particles describes the theory and practice of data an

Spis treści

Basic Analysis Principles

Sedimentation of Discrete Non-Interacting Particles

Properties of Sedimentation Coefficient Distributions

Distributions Of Non-Diffusing Particles

Distributions of Diffusing Particles

Sedimentation Coefficient Distributions from Boundary Derivatives and Extrapolations

Multi-Component Distributions

Practical Analysis of Non-Interacting Systems

Appendix A: Numerical Solutions of the Lamm Equation

Appendix B: Calculating Distributions

O autorze

Dr. Schuck obtained his Ph.D. from the Goethe-University Frankfurt am Main, Germany, where he worked on interactions of integral proteins of the erythrocyte membrane using analytical ultracentrifugation. He received his post-doctoral research training in physical biochemistry with Dr. Allen Minton at NIDDK, and joined the Bioengineering and Physical Science Program of NCRR as a Research Fellow in 1997. He is currently a Earl Stadtman Tenure-Track Investigator and Chief of the Dynamics of Macromoleular Assembly Section, Laboratory of Cellular Imaging and Macromolecular Biophysics at the National Institute of Biomedical Imaging and Bioengineering, National Institutes of Health.