1. Introduction of bioprocess: From 1 to 100 2. Screening and characterizing of prebiotics for plant biomass fermentation 3. Designing and engineering synthetic microbiota for plant biomass fermentation to obtain bioactive compounds 4. Scale-up and Scale-down fermentation for the commercial production of plant-derived bioactive compounds 5. Fermentation of plant biomass using pure probiotics for the commercial production of plant-derived bioactive compounds 6. Fermentation of plant biomass using synthetic microbiota for the commercial production of plant-derived bioactive compounds 7. Fermentation with engineered microbes for the commercial production of plant-derived bioactive compounds 8. Optimization parameters for efficient scale-up fermentation process 9. Development of economic extraction and purification process for plant-derived bioactive compounds 10. Balance of titer, rate, and yield during production of plant-derived bioactive compounds 11. Economic evaluation of the scale-up and chemical bioprocess 12. Examples for successful commercial production of plant-derived bioactive compounds 13. The principles to development novel scale-up bioprocess 14. Scale-up and chemical process development for production of plant-derived bioactive compounds commercially using microbes: Challenges and prospects