Scabies

ISBN-13: 9783031260698 / Angielski / Twarda / 2023

Katja Fischer; Olivier Chosidow

Opis

This edited volume covers all aspects of the Neglected Tropical Disease Scabies. The contributions are organised into four themed parts. The first part reviews the history of the disease and its treatment and management, part two is dedicated to parasitology and basic research on the disease causing parasite, Sarcoptes scabei. Epidemiology and disease burden including public health issues are discussed in the third part in detail. The last section of the book is covering clinical manifestation and management. 

This volume is the first one of its kind, providing an insight into all aspects of the skin disease which is causing considerable morbidity and mortality. Chapters are all written by dedicated experts in their respective area of interest making the publication a must have for all scientists and clinicians as well as public  health specialists dedicated to Scabies research in any aspect.

Spis treści

Preface.- History of scabies.- Parasitology and Basic research.- Biology of scabies (systematics, morphology, life cycle).- Genotyping and Host Specificity.- Host immune response to scabies.- Scabies Mite Biochemical Research – an overview.- Scabies multi-omics as a way to bring the basic science up to speed.- Scabies associated microbiota.- Experimental animal models.- Epidemiology and burden of scabies – Public health issues.- Epidemiology and risk factors.- Public health issues, Scabies surveillance and awareness.- Scabies and secondary infections.- Scabies, the 17th NTD in the WHO list - Role of IACS.- Clinical manifestations and management.- Clinic – classic scabies and special forms (except pediatric).- Clinic  – pediatric.- Diagnosis of Scabies.- Parasitological diagnosis.- Non-invasive diagnosis.- Potential for sensitive and simple molecular diagnostic tools  -blood tests for scabies.- Animal scabies.- Treatment management (adults and children) and drug resistance.- Scabies mass treatment in poor-resource countries.- Management in health care facilities.- New treatment solutions.

O autorze

Dr Katja Fischer is a Group Leader at the QIMR Berghofer Medical Research Institute in Brisbane. She completed her undergraduate training as a molecular parasitologist at the University of Freiburg, Germany, followed by a PhD in molecular biology of malaria parasites at the University of Würzburg, Germany, followed by post doc positions at QIMR Berghofer MRI. She became Laboratory Head in 2007 and Group Leader in 2013. Her laboratory at the QIMR Berghofer MRI is one of very few groups worldwide providing since 2003 continuously crucial biomedical research towards reducing scabies and associated secondary infections.

Olivier CHOSIDOW is Professor of Dermatology and past chair of the Department of Dermatology at the University Paris-est Creteil, Henri Mondor Hospital, Creteil, France. Dermatologist since 1987, he obtained his PhD in clinical pharmacology in 1995 and graduated in clinical epidemiology in 1997. He was President of the French Society of Dermatology in 2013-2014, is an external advisor of the ILDS (International League of Dermatological Societies)-WHO committee, belongs to the IACS (International Alliance for the Control of Scabies) steering committee, and is an ISD (International Society of Dermatology) board member. He received an EADV (European Academy of Dermatology and Venereology) clinical care award in 2015 and an ILDS certificate of appreciation in 2016.

He is mainly involved in Skin Infectious Diseases since his internship including scabies and other ectoparasitic diseases (and necrotizing fasciitis, a potential complication of scabies). He is heading numerous randomized clinical trials, mostly academic, granted by the French Ministry of Health. As a clinician researcher, he authored more than 550 articles, including NEJM, Lancet/Lancet ID, BMJ, JAAD, JAMA Dermatology, BJD, JID, IJD, and delivered more than 600 talks at the national, European and international level.