Role of Rosiglitazone & Felodipine in attenuation of cardiac fibrosis

ISBN-13: 9786139921515 / Angielski / Miękka / 2018 / 120 str.

Omnia Aly; Mohamed M. Hafez; Hanan Hassan Zaki

Opis

Cardiac fibrosis is a pathological feature common to numerous forms of heart disease, including myocardial infarction; ischemic, dilated, and hypertrophic cardiomyopathies; and heart failure. The cellular basis of fibrosis is the adverse accumulation of collagens and other ECM proteins, which impairs ventricular function and predisposes the heart to arrhythmias. The purposes of this study are to clarify the adverse effects of diabetes mellitus and hypertension on cardiac manifestations as well as to focus on the characteristic features of cardiac remodeling induced by diabetes and hypertension particularly cardiac fibrosis to address the molecular mechanism underlying them.

O autorze

Aly, Omnia
Mohamed M. Hafez, lecturer of Biochemistry and Molecular Biology, Faculty of Pharmacy, Ahram Canadian University (ACU), Egypt. A member in editorial team of The Journal of Nephrology and Therapeutics. A reviewer in many international journals as OMICS journals and BIO MED journals. I have many international papers in many international journals. .