Role of Folliculo-Luteal Function in Human Reproduction

ISBN-13: 9783319395395 / Angielski / Twarda / 2016 / 200 str.

Gyorgy Siklosi

Opis

This book is the first to explain fully the crucial role of folliculo-luteal function in recurrent miscarriage, unexplained infertility, preterm birth, intrauterine growth retardation, preeclampsia, random chromosomal abnormalities, and age-related reproductive disorders. In addition it describes treatments to avoid these conditions and proposes a novel method, hormonal wedge resection, that can successfully cure infertility associated with polycystic ovary syndrome. Importantly, the conclusions drawn in this book are based on the therapeutic results observed in a representative patient population. The method developed by the author to quantitatively diagnose the hormonal insufficiency of ovulatory cycles (folliculo-luteal insufficiency, FLI) has made it possible to recognize the formerly unclear importance of this function in human reproduction. Folliculo-luteal function determines the conditions of placentation and thus the features of the developed placenta and the outcome of pregnancy. Different grades of FLI are associated with consequences of varying severity that can be prevented by normalization of folliculo-luteal function prior to conception. This book will be required reading for all obstetricians and gynecologists."

Spis treści

Patients and methods.- Hormonal characteristics of the physiological menstrual cycle.- Causes and pathomechanism of folliculo-luteal insufficiency.- Treatment of folliculo-luteal insufficiency.- The real cause and the successful treatment of recurrent miscarriage.- The role of folliculo-luteal insufficiency in unexplained infertility.- The relationship between folliculo-luteal function and the outcome of pregnancy.- Preventing preterm birth, intrauterine growth retardation (IUGR) and preeclampsia by normalization of placentation.- The role of folliculo-luteal insufficiency in the emergence of random chromosomal abnormalities.- The role of folliculo-luteal function in the emergence of age-related reproductive disorders.- “Hormonal wedge resection”: an effective treatment method of anovulatory infertility associated with polycystic ovary syndrome.- The beneficial effects of preconceptional normalization of folliculo-luteal function on reproduction.

O autorze

György Siklósi graduated from Semmelweis University, Budapest with the Award “Sub Auspiciis Rei Publicae Popularis” and a Gold Ring from the President of the Republic of Hungary. Since graduating he has worked in the 2nd Department of Obstetrics and Gynecology of Semmelweis University, Budapest. He was the first deputy director of the clinic for 13 years and head of the first Department of Gynecological Endocrinology in Hungary for 15 years. He has been interested in reproductive endocrinology since the beginning of his scientific work. To date Dr. Siklósi has published 130 scientific articles in Hungarian and foreign languages and made 150 scientific presentations in Hungarian and at international forums. He obtained his PhD in 1986 for a thesis on hyperandrogenic conditions in women and associated reproductive dysfunctions, and gained a scientific degree in medicine from the Hungarian Academy of Sciences in 1996 by successfully defending his thesis entitled A luteális funkció meghatározó szerepe az emberi reprodukcióban (“The fundamental role of luteal function in human reproduction”). He was among the first individuals to gain Habilitation in 1994 in Hungary. He became a university professor in 1997. He was an elected member of the College of Obstetrics and Gynecology in four cycles and the Secretary General of the Hungarian Society of Obstetrics and Gynecology in two cycles.