ISBN-13: 9783659961786 / Angielski / Miękka / 2016 / 168 str.
Arthritis is one of the most common causes of joint pain and physical disability worldwide; including Iraq, Juvenile Idiopathic Arthritis (JIA) and Rheumatoid Arthritis (RA) are the two major groups of arthritis characterized by chronic joint inflammation, in which cytokines may have a pathogenic role. Therefore, the present study aimed to determine serum level of 12 cytokines (IL-1 , IL-1RA, IL-2, IL-4, IL-10, IL-12, IL-17A, IL-22, IL-31, IL-33, IFN-Gamma and TNF- ) in JIA and RA patients. A correlation with disease severity and activity, type of administrated therapy and clinical subtypes of JIA was also assessed.