Role of Connexin 43 in Ischemia-Reperfusion Injury and Arrhythmias

ISBN-13: 9783659461507 / Angielski / Miękka / 2013 / 192 str.

Sanchez-Garcia Jose Antonio

Opis

This study demonstrates an important, and previously unknown, specific role of Cx43 in myocardial energetic metabolism, tolerance to ischemia-reperfusion injury and in endogenous cardioprotection. GJ and Cx43 can become interesting pharmacological targets to improve the clinical outcome in patients with ischemic heart disease. However, translation should wait until the proarrhythmic effects of these treatments are solved.

O autorze

Doctor in Science. Well-developed skills in ischemia reperfusion experiments performed in isolated mice and rat hearts, arrhythmogenesis studies and biochemical techniques, such as Western Blot, PCR analysis, immunohistology, etc. Self-motivated, hard-working. In-depth understanding of Microsoft Office and other useful computer programmes.