Rifaximin: From Chemistry to Clinical Applications

ISBN-13: 9786208172329 / Angielski / Miękka / 2024 / 136 str.

Shibani Raut

Opis

"Rifaximin: From Chemistry to Clinical Applications" provides a comprehensive overview of Rifaximin, a semi-synthetic antibiotic derived from rifamycin, known for its non-systemic properties and its significant role in treating gastrointestinal disorders like hepatic encephalopathy, small intestinal bacterial overgrowth (SIBO), and inflammatory bowel disease (IBD). The book explores Rifaximin's chemical structure, pharmacological profile, synthesis, and analytical techniques for drug quality. It highlights the drug's clinical applications, mechanism of action, and role in combination therapies, while addressing issues like drug resistance, pharmacogenomics, safety, and formulation challenges. Special populations such as pediatric and geriatric patients are considered, along with Rifaximin's economic and patent landscape. The book concludes with insights into future research, challenges, and controversies surrounding the drug, making it a valuable resource for healthcare professionals, researchers, and students.