Review: Synthesis and Biological Importance of Benzofuran Derivatives

ISBN-13: 9783659934025 / Angielski / Miękka / 2016 / 84 str.

Bapu Thorat; Ramesh Yamgar; Kishor More

Opis

Benzofurans and their derivatives are present in remarkable amounts in plants, although their presence has also been detected in microorganisms and animal sources. It was synthesized from variety of substituted phenols, iodophenols, o-hydroxybenzaldehydes, o-hydroxyacetophenone, etc and study their biological activity. It was one of the most biological potent skeleton. Several studies have revealed that various substituents on the benzofuran core structure influence different biological activities such as anti-tumor, anti-coagulant, anti-inflammatory, anti-oxidant, anti-HIV and anti-bacterial.

O autorze

Dr. Bapu R Thorat is Assistant Professor in Organic Chemistry working under Higher Education Department, Government of Maharashtra, Maharashtra State, India. He's area of interest of research is Drug Design, Molecular Modeling and Synthetic Chemistry. He published more than 40 papers in research journals on various topics.