Research and Clinical Applications of Targeting Gastric Neoplasms

ISBN-13: 9780323855631 / Angielski / Miękka / 2021

Brendan Jenkins

Spis treści

1. Stomach corpus stem cells in homeostasis, tissue repair, and cancer 2. The role of inflammation in gastric tumorigenesis 3. Unravelling the pro-tumorigenic role of innate immune pattern recognition receptors in the gastric compartment 4. Helicobacter pylori-induced gastric carcinogenesis 5. The role of Helicobacter pylori CagA oncoprotein in neoplastic transformation of gastric epithelial cells 6. Epigenetic aberrations by Epstein-Barr virus infection to develop gastric cancer 7. In vivo and in vitro models of gastric cancer 8. Premalignant lesions of the stomach and management of early neoplastic lesions 9. Updated perspective and directions on hereditary diffuse gastric cancer 10. Systems biology and molecular characterization of subtypes to guide targeted therapies in gastric cancer 11. Current state of chemotherapy and immunotherapy regimens in gastric cancer 12. Case studies highlighting the multiple facets of gastric cancer: one diagnosis, multiple approaches1. Stomach corpus stem cells in homeostasis, tissue repair, and cancer 2. The role of inflammation in gastric tumorigenesis 3. Unravelling the pro-tumorigenic role of innate immune pattern recognition receptors in the gastric compartment 4. Helicobacter pylori-induced gastric carcinogenesis 5. The role of Helicobacter pylori CagA oncoprotein in neoplastic transformation of gastric epithelial cells 6. Epigenetic aberrations by Epstein-Barr virus infection to develop gastric cancer 7. In vivo and in vitro models of gastric cancer 8. Premalignant lesions of the stomach and management of early neoplastic lesions 9. Updated perspective and directions on hereditary diffuse gastric cancer 10. Systems biology and molecular characterization of subtypes to guide targeted therapies in gastric cancer 11. Current state of chemotherapy and immunotherapy regimens in gastric cancer 12. Case studies highlighting the multiple facets of gastric cancer: one diagnosis, multiple approaches