Regulatory Mechanisms of Synaptic Transmission

ISBN-13: 9781468439700 / Angielski / Miękka / 2012 / 422 str.

R. Tapia

Opis

This book, which originated in the presentations of a symposium sponsored by the Universidad Nacional Autonoma de Mexico, held in Mexico City on April 14-16, 1980, represents an attempt to analyze some of the most relevant aspects of synaptic transmission. This topic was chosen on the strong belief that the progress of the neurosciences depends to a great extent on the understanding of the basic mechanisms of synaptic function. Rather than selecting only a specific approach or speciality, the book intends to cover this field in a multi disciplinary way. This means that neurochemical, neurophysiological and morphological studies are mingled throughout the book, which hopefully will help the reader to integrate the different faces of the same problem. Across the book the presynaptic component of synaptic transmission and its regulation is stressed much more than the postsynaptic phenomena. Although this might be a limitation, it has the advantage of increasing the focus of the book on a series of events which are gaining importance and interest every day."

Spis treści

Catecholamines and Endorphins as Neurotransmitters and Neuromodulators.- Enkephalin Release from the Globus Pallidus: In Vitro and In Vivo Studies.- Acidic Amino Acids as Excitatory Transmitters.- Glutamergic Neurons: Localization and Release of the Transmitter.- GABAergic Synapses: Distribution and Interactions with other Neurotransmitter Systems in the Brain.- GABA Release In Vivo and In Vitro: Responses to Physiological and Chemical Stimuli.- Taurine as a Neuromodulator: Its Action on Calcium Fluxes and Neurotransmitter Release.- A Presynaptic Voltage Clamp Study in the Squid Stellate Ganglion.- Calcium Transport and the Release of Neurotransmitters: Effects of Drugs In Vivo and In Vitro.- On the Role of Mitochondria in Neurotransmitter Release.- Calcium, Calmodulin, and Synaptic Function: Modulation of Neurotransmitter Release, Nerve Terminal Protein Phosphorylation, and Synaptic Vesicle Morphology by Calcium and Calmodulin.- Brain Clathrin: A Study of its Properties.- Effect of Nerve Growth Factor on Microtubules: Evidence for a Protective Action against Depolymerization Induced by Calcium Ions or Cold Treatment.- Selective Re-Innervation of Twitch and Slow Muscle Fibers of the Frog.- Presynaptic Control of Information Transmission in the Vertebrate Spinal Cord.- Synaptic Changes Induced by Optic Chiasm Low Intensity Repetitive Electrical Stimulation (The Kindling Effect).- Calcium Current Modulation as a Mechanism in the Synaptic Plasticity Underlying Habituation and Sensitization in Aplysia.- Modulation of Synaptic Plasticity: A Theoretical Approach.- Regulatory Mechanisms of REM Sleep in the Cat.- List of Contributors.