Regenerative Medicine Technology: On-A-Chip Applications for Disease Modeling, Drug Discovery and Personalized Medicine

ISBN-13: 9781498711913 / Angielski / Twarda / 2016 / 428 str.

Sean V. Murphy; Anthony Atala

Opis

This book covers the technologies necessary to develop organ-on-a-chip systems, including microfabrication, 3D bioprinting, 3D cell culture techniques, biosensor design and microelectronics, microfluidics, data collection, and predictive analysis. It details specific tissue types that have been developed for disease modeling and drug discovery applications, including lung, liver, heart, skin, and kidney "on-a-chip" as well as recent progress in designing an entire "body-on-a-chip" system. It also provides an overview of other current and potential applications of these systems.

Spis treści

Introduction. Microfabrication and 3D Bioprinting. 3D Cell Culture/Tissue Spheroids. Biosensors and Microelectronics. Microfluidics. Big Data/Predictive Analysis. Lab-on-a-Chip. Lung-on-a-Chip. Liver-on-a-Chip. Heart-on-a-Chip. Skin-on-a-Chip. Kidney-on-a-Chip. Body-on-a-Chip. Liver Cancer-on-a-Chip. Lung Cancer-on-a-Chip. Breast Cancer-on-a-Chip. Cancer Metastasis-on-a-Chip. Cancer Microenvironment-on-a-Chip. Disease Modeling. Toxicology Testing. Detection of Bioweapon Pathogens. Personalized Medicine.

O autorze

Sean V. Murphy, Anthony Atala