Regenerative Medicine: Emerging Techniques to Translation Approaches

ISBN-13: 9789811960079 / Angielski / Twarda / 2023 / 390 str.

Nishant Chakravorty; Praphulla Chandra Shukla

Opis

This book focuses on the recent innovations and therapeutic potentials of regenerative medicine and discusses the applications of stem cells, biomaterials, and tissue engineering in regenerative medicine. The book covers essential aspects of regenerative medicine, including tissue microenvironment, immunological perspectives, stem, and non-stem cell-mediated approaches, imaging techniques, biomarkers, and 3D printing technology. It also reviews the applications of biosensing technologies in regenerative medicine, including biomanufacturing, organ-on-a-chip technologies, and as indicators of therapeutic efficacy. Further, it focuses on the regenerative medicine approaches for diseases of the central nervous system. It also provides the therapeutic potential of regenerative medicine to improve soft tissue and wound healing, cardiovascular, neural, bone, and orofacial regeneration.​

Spis treści

Chapter 1. Regeneration and tissue microenvironment.- Chapter 2. Non stem cell mediated tissue regeneration and repair.- Chapter 3. Immunological Perspectives Involved in Tissue Engineering.- Chapter 4. Advances in Medical Imaging for Wound Repair and Regenerative Medicine.- Chapter 5. Role of Biosensors in Regenerative Therapeutics: Past, Present & Future Prospects.- Chapter 6. Acute and Chronic Wound Management: Assessment, Therapy and Monitoring Strategies.- Chapter 7. Stem cells and therapies in cardiac regeneration.- Chapter 8. Hydrogel-based Tissue-mimics for Vascular Regeneration and Tumor Angiogenesis.- Chapter 9. Advances in 3D Printing Technology for Tissue Engineering.- Chapter 10. Adult Neurogenesis: A Potential Target for Regenerative Medicine.- Chapter 11. Regenerative approaches in the nervous system.- Chapter 12. Prenatal interventions for the treatment of congenital disorders.- Chapter 13. Understanding LncRNAs in biomaterials development for osteointegration.- Chapter 14. Current approaches in vertical bone augmentation and large bone deficiencies in the oro-facial region.- Chapter 15. In-vitro and in-vivo tracking of cell-biomaterial interaction to monitor the process of bone regeneration.- Chapter 16. The Prospects of RNAs and Common Significant Pathways in Cancer Therapy and Regenerative Medicine.

O autorze

Dr. Nishant Chakravorty leads the Regenerative Medicine lab as a faculty member at the School of Medical Science and Technology, Indian Institute of Technology Kharagpur (India). He has earlier served as a Clinical Specialist with Philips India Ltd (2014-2015). Dr. Chakravorty is a physician-scientist by training (MBBS, Masters in Med. Sci. & Tech.) with a PhD from Queensland University of Technology (QUT), Australia (2014). His research interests involve utilization of the concepts of cellular and molecular biology, biomaterials and tissue engineering to study human pathophysiological conditions. He has several international research publications, book chapters, and conference presentations to his credit. He is an Editorial Board member of the journal Molecular Biology Reports and also serves as a reviewer for several international journals. Dr. Chakravorty is a selected Member of India’s one and only young science academy, Indian National Young Academy of Sciences (INYAS) and is an elected Member of Royal Society of Biology, UK. He is also the recipient of several awards notably, Outstanding Doctoral Thesis Award - Executive Dean’s Commendation Award for 2014 (Science and Engineering Faculty, QUT, Australia) and Institute Silver Medal, (IIT Kharagpur-2010). He is a Life Member of Indian Society of Hematology and Blood Transfusion, Bengal Society of Haematology (BSH), India and Eastern Haematology Group, India.

Dr Praphulla Chandra Shukla is a faculty of School of Medical Science and Technology, IIT Kharagpur. He was earlier associated with Charite´ Medical University Berlin, Germany (2014-2016), BITS Pilani, India (2012-2014), Whitaker Cardiovascular Institute, Boston University, Boston (2011-2012) and University of Toronto (2006-2011). His research interests are myocardial damage and regeneration, endothelial cells transformation, atherosclerosis, cardiomyocyte cell cycle and epigenetics. He has been selected for various fellowships and been the finalist for Young Investigator Awards from American College of Cardiology, American Heart Association. He has published more than 20 international peer-reviewed papers. He is also active member of various societies such as German Cardiac Society, Canadian and American Heart Association as well as American College of Cardiology.

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