Receptors and Ligands in Neurological Disorders

ISBN-13: 9780521307208 / Angielski / Twarda / 1988 / 340 str.

Amar K. Sen;Tyrone Lee

Opis

Fifteen chapters, written by experts in the field, summarize current studies that involve receptors and ligands in neurological disorders. The advance in the study of receptors in general enables investigators to explore the mechanism of action of psychotropic drugs and to minimize their side effects. It will lead to the study of molecular events and an understanding of the nature and cause of the various diseases and to more accurate diagnoses that may give more effective therapeutic treatments. Topics discussed include the role of central dopamine in movement disorders, aluminum and Alzheimer's disease, receptor binding in the kindling model of epilepsy, and cholinergic neurons in Huntington's disease. The chapters have been carefully edited for a wide appeal to pharmacologists, neurologists, and neuroscientists.

Spis treści

Preface; Introduction; 1. Cnolinergic neurons in Huntington's disease K. G. Lloyd and C. J. Carter; 2. GABA deficiency in Humtington's disease Thomas L. Perry; 3. The role of cental dopamine in movement disorders Menek Goldstein and Emanual Meller; 4. Tardive dyskinesia - a historical review Caroline M. Tanner and Harold L. Klawans; 5. Gilles de la tourette syndrome Jack W. Schweitzer and Arnold J. Friedhoff; 6. Aluminium and Alzheimer's disease D. R. Crapper McLachlan; 7. Cortical neurotransmitter receptors: distribution and involvement in Alzheimer's disease E. K. Parry and J. M. Candy; 8. Neurotransmitter receptors in normal human aging and Alzheimer's disease David G. Morgan, Patrick C. May and Caleb E. Finch; 9. Acetylocholine receptor in myasthenia gravis R. J. Boegman and K. K. Wan; 10. Receptor binding in the kindling model of epilepsy W. M. Burnham; 11. Imagining of regional celebral metabolism and blood flow in epilepsy George J. Siegel, Bassel Abou-Khalil and J. Chris Sackellares; 12. A review of the attentional deficit disorder of chilhood Lisa A. Raskin, Sally E. Shaywitz, Bennett A. Shaywitz, George M. Anderson, James F. Leckman and Donald J. Cohen; 13. Receptor studies in sleep and sleep disorders Mortimer Mamelak; 14. Receptor localization in neuropsychiatry James K. Wamsley and Ted M. Dawson; 15. Brain tissue transplantation: applications to neurological research Stephen B. Dunnett and Anders Björklund; Index.