Ranaviruses: Lethal Pathogens of Ectothermic Vertebrates

ISBN-13: 9783319357775 / Angielski / Miękka / 2016 / 246 str.

Matthew J. Gray; V. Gregory Chinchar

Opis

This is the first book on ranaviruses. Ranaviruses are double-stranded DNA viruses that cause hemorrhagic disease in amphibians, reptiles, and fish. They have caused mass die-offs of ectothermic vertebrates in wild and captive populations around the globe. There is evidence that this pathogen is emerging and responsible for population declines in certain locations. Considering that amphibians and freshwater turtles are suitable hosts and the most imperiled vertebrate taxa in the world, ranaviruses can have significant impacts on biodiversity and ecosystem function. Additionally, many fish that are raised in aquaculture facilities and traded internationally are suitable hosts; thus, the potential economic impact of ranaviruses is significant. Ranaviruses also serve as a model for replication and gene function of large double-stranded DNA viruses. There is an urgent need to assemble the contemporary information on ranaviruses and provide guidance on how to assess their threats in populations. Through the Global Ranavirus Consortium, 24 experts from six countries were organize to write this volume, the first book on ranaviruses. The book begins with a discussion on the global extent of ranaviruses, case histories of infection and disease in ectothermic vertebrates, and current phylogeny. Basic principles of ranavirus ecology and evolution are covered next, with a focus on host-pathogen interactions and how the virus emerges in its environment. There are two chapters that will discuss the molecular biology of ranaviruses, host response to infection, and the genes responsible for immune system evasion. One chapter establishes standards for testing for infection and diagnosing ranaviral disease. The book ends by providing guidance on how to design ranavirus surveillance studies and analyze data to determine risk, and discussing the role of the Global Ranavirus Consortium in organizing research and outreach activities.

Recenzje

"Matthew J. Gray (Univ. of Tennessee) and V. Gregory Chinchar (Univ of Mississippi) have compiled a comprehensive and thorough treatise on ranaviruses, an understudied group of viruses that infect fish, amphibians, and reptiles. ... This book is an invaluable source for wildlife biologists seeking to understand a potentially important group of viruses and for virologists interested in knowing about the impact of these viruses in the natural world. Summing Up: Highly recommended. Upper-division undergraduates through professionals/practitioners." (M. S. Kainz, Choice, Vol. 53 (3), November, 2015)

Spis treści

Table of Contents and Lead Authors:

 

I.                   Introduction

By Matt Gray and Greg Chinchar

 

II.                Distribution and Phylogeny of Ranaviruses

By Amanda Duffus, Thomas Waltzek, Rachel Marschang, and others

§ Amphibians (Amanda)

§ Fish (Tom)

§ Reptiles (Rachel)

 

III.             Host-pathogen Ecology and Evolution

By Jesse Brunner and others

 

IV.             Molecular Biology of Ranaviruses

By Greg Chinchar and others

 

V.                Immune Evasion and Host Immunity

By Jacques Robert and others

 

VI.             Pathology and Diagnostics

By Debra Miller, Allan Pessier, and others

 

VII.          Design and Analysis of Ranavirus Studies

By Matt Gray and others

 

VIII.       Global Ranavirus Consortium

By Matt Gray, Jesse Brunner, Amanda Duffus and others

O autorze

Dr. Matthew J. Gray serves as Associate Professor for the Center for Wildlife Health at the University of Tenessee Department of Forestry, Wildlife, and Fisheries. He is the Director of the Global Ranavirus Consortium.

V. Gregory Chinchar is Professor of Microbiology at the University of Mississippi Medical Center in Jackson, Mississippi. He serves as Honorary Advisor to the Global Ranavirus Consortium.

Blurb

The first book of its kind, this work discusses the global extent of ranaviruses, principles of ranavirus ecology and evolution. The research included provides guidance on designing ranavirus surveillance studies to determine risk. Ranaviruses are are double-stranded DNA viruses that cause hemorrhagic disease in amphibians, reptiles, and fish. Ranaviruses have caused mass die-offs of ectothermic vertebrates in wild and captive populations around the globe. Ranaviruses: Lethal Pathogens of Ectothermic Vertebrates serves an urgent need to assemble the contemporary information on ranaviruses, and provide guidance on how to assess this threat in populations.