Quality Control of Cellular Protein in Neurodegenerative Disorders

ISBN-13: 9781799813170 / Angielski / Twarda / 2020 / 260 str.

Md. Sahab Uddin;Ghulam Md Ashraf

Opis

A hallmark of neurodegenerative proteinopathies is the formation of misfolded protein aggregates that cause cellular toxicity. Though multiple factors like aging, oxidative stress, gene inconsistency, etc. are responsible for the dysfunction of the protein quality control system, targeting protein quality control has become an auspicious approach to block the propagation of neurodegeneration. Quality Control of Cellular Protein in Neurodegenerative Disorders provides diverse aspects exploring the theoretical and practical methods of protein quality control systems and potential therapeutic approaches to halt the development and propagation of neurodegenerative disorders. Featuring coverage on a broad range of topics such as cellular chaperones, protein folding, and stress signaling, this book is ideally designed for neurobiologists, neuropsychologists, neurophysiologists, medical professionals, neuropathologists, researchers, academicians, students, and practitioners engaged in studies of the protein quality control system in neuronal cells.