Pulsatile Drug Delivery System - Current Scenario

ISBN-13: 9783659158322 / Angielski / Miękka / 2012 / 60 str.

Hitesh Chopra

Opis

Pulsatile Drug Delivery Systems are gaining a lot of interest as they deliver the drug at the right place at the right time and in the right amount, thus providing spatial and temporal delivery and increasing patient compliance. These systems are designed according to the circadian rhythm of the body. The principle rationale for the use of pulsatile release of the drugs is where a constant drug release is not desired. A pulse has to be designed in such a way that a complete and rapid drug release is achieved after the lag time. Various systems like capsular systems, osmotic systems, single- and multiple-unit systems based on the use of soluble or erodible polymer coating and use of rupturable membranes have been dealt with in the article. It summarizes the latest technological developments, formulation parameters, and release profiles of these systems. These systems are beneficial for the drugs having chronopharmacological behavior where night time dosing is required, such as anti-arhythmic and anti-asthmatic.

O autorze

Author is the B.pharma graduate in the year 2012. He had attended various national and international conferences in the graduation.He had presented various posters on the topic Microspheres and Pulsatile Drug Delivery System. He had done the project on the Preparation and Evaluation of Metformin Microspheres prepared by Double Emulsion technique.