Pulmonary and Critical Care Considerations of Hematopoietic Stem Cell Transplantation

ISBN-13: 9783031287961 / Angielski

Ayman O. Soubani

Opis

This book serves as a guide to the pulmonary and critical care complications  of hematopoietic stem cell transplantation (HSCT). HSCT is an important therapeutic modality for a variety of malignant and non-malignant conditions. The outcomes of these patients have been improving and the number of HSCT cases is increasing around the world. These patients, however, continue to have post-transplant complications related to conditioning regimens and graft vs. host disease. Pulmonary complications following HSCT remain a major cause of morbidity and mortality in this patient population.The book begins with an overview of HSCT and graft vs. host disease. Chapters then cover particular complications, including immunological changes in lungs, diffuse alveolar hemorrhage, bronchiolitis obliterans and pulmonary fibrosis. Other complications, including neurologic, renal, gastrointestinal, and cardiac, are covered. Chapters are comprehensive and consistent with each defining the scope of the complication, epidemiology, risk factors, diagnostic approach, management, outcome and predictors of outcome, and future directions. The book provides insight as well on matters that arise during the care of HSCT patients such as provider burnout, nursing care, intensive care unit organization, nutritional support, and pulmonary and physical rehabilitation. This is an ideal guide for pulmonologists, critical care physicians, transplant specialists, oncologists, and relevant trainees caring for patients who have undergone HSCT.

Spis treści

HSCT- overview- types, indications, epidemiology, outcomes

Graft vs Host Disease- manifestations and management

Immunological changes in lungs following HSCT

Spectrum of pulmonary complications following HSCT

Pre-transplant pulmonary evaluation

Diagnostic evaluation of pulmonary diseases following HSCT

Chest radiology in HSCT

Bacterial respiratory infections

Aspergillosis

Other fungal respiratory infections

CMV pneumonia

Respiratory viral infections

Emerging infections

Diffuse alveolar haemorrhage

Engraftment Syndrome

Idiopathic pneumonia syndrome

Bronchiolitis obliterans syndrome

Pulmonary fibrosis

Other non-infectious pulmonary complications

Co-morbid pulmonary diseases in HSCT patient

Pulmonary rehabilitation and HSCT

Lung transplant for HSCT patient

Critical care outcomes of HSCT patient

Respiratory support of critically ill HSCT patient- MV, NIV, HFNC

Cardiac considerations in critically ill HSCT patient

Renal considerations in critically ill HSCT

GI and hepatic considerations in critically ill HSCT patient

Neurologic considerations in critically ill HSCT patient

Hematologic considerations in critically ill HSCT patient

Critical care nursing of HSCT patient

Supportive care and HSCT patient

Coordinating care of HSCT with pulmonary and critical care illness-outpatient/BMT-ICU care units/ multidisciplinary ICU rounds/ telemedicine.

O autorze

Ayman O. Soubani, MD is Professor of Medicine at Wayne State University School of Medicine in Detroit, Michigan, USA. He also serves as Medical Director, Medical ICUs, Detroit Medical Center Adult Central Campus; Service Chief, Pulmonary and Critical Care, Karmanos Cancer Center; and Medical Director, Critical Care Service, Karmanos Cancer Center.