Protective Effect of Cumin and Coriander on Profenofos : Antidote effect of Cumin and Coriander

ISBN-13: 9783659261367 / Angielski / Miękka / 2012 / 96 str.

Arun Kumar; Ranjit Kumar; Mohammad Ali

Opis

Profenofos [0-4-bromo-2-chlorophenyl -0-ethyl S-propyi phosphorothioate] is a broad spectrum organophosphate insecticide and acaricide. Its main physiological effect is the inhibition of cholinesterase activity in insects. In the present study Profenofos @ 25 mg/kg b.w was administered to the Swiss albino mice for 4 weeks to observe the Profenofos induced hepatotoxicity. Upon this group Cuminum cyminum (Cumin) and Coriandrum sativum (Coriander) were administered for 4 weeks to observe its antidote effect. The study through various paramaters shows that Cumin and Coriander play vital role to combat the Profenofos induced hepatotoxicity thus showing its protective effect.

O autorze

Dr. Arun Kumar has done his Ph.D in Zoology in 2008 from Patna University, Patna, Bihar, India and is presently working at Mahavir Cancer Institute & Research Centre, Patna, Bihar, India as Scientist. He has been awarded with Prof. G.P.Talwar Gold medal in 2007 and many other awards in his academic career and has published several research papers.