Progress in Diagnostics and Therapy of Prostatic Cancer

ISBN-13: 9783540601951 / Angielski / Miękka / 1996 / 79 str.

Peeling; W. B. Peeling; Hermann Becker

Opis

There is now increasing awareness by the general public in European countries that prostate cancer is a serious threat to health, and this has created higher expectations for improved and more effective methods for detecting and treating the disease. However, urologists are very conscious of the limitations of the diagnostic methods that are available and are even more concerned about the apparent lack of therapeutic advances made during the past 50 years since Huggins discovered the fundamental principles of endocrine treatment for is theo prostate cancer. Recent efforts to detect the disease when it retically "curable" have been successful, certainly in the USA, but this has highlighted our uncertainty about the best treatment for early stage prostate cancer, and there is no doubt that radical pro statectomy is sometimes carried out on men who may not be threa tened by their illness. While it is generally accepted that many men with prostate cancer will die of old age rather than this malignancy, it cannot be ignored that this disease kills many others in a process that is frequently lingering, miserable, and humiliating, not only for the victim but also his family. There are many important issues about prostate cancer that remain unclear at the present time, some of which are addressed by the reviews in this book. The debate about early detection and screening can arouse considerable heat in otherwise placid urological mee tings."

Spis treści

and New Aspects of the Biology of Prostate Carcinoma.- Value of Digital Rectal Examination, Determination of Prostate-Specific Antigen Concentration and the Use of Transrectal Ultrasonography.- Screening for Early Prostate Cancer.- Carcinoma of the Prostate: Science and Treatment.- Neoadjuvant Androgen Deprivation Before Radical Prostatectomy for Stage T3 Cancer.- Partial Versus Complete Androgen Deprivation.- Monthly Microcapsule Depot Form of Leuprorelin: Animal Studies and Internal Structure of Microcapsules.- A Clinical Study Investigating Overall Patient Acceptability of Leuprorelin in Acetate for the Treatment of Advanced Prostatic Cancer.- Efficacy of Leuprorelin Acetate Depot in the Treatment of Prostatic Cancer: Results of a Long-Term Follow-Up Study.

Blurb

The progress made in the diagnosis of prostate carcinoma with the introduction of transrectal ultrasound (TRUS), PSA determination, and ultrasound-guided prostate biopsy as well as improved operating techniques have led to a considerable increase in the number of radical prostate operations being performed and thus increased the chances of success of curative treatment in many patients. The use of neoadjuvant endocrine therapy before radical prostatectomy is still a matter of debate. It will certainly only be possible to make a final judgement on the basis of long-term observations. This book takes into account that only an international exchange of new findings can create the necessary conditions for improved treatment.