Prognostic and Predictive Factors in Gynecologic Cancers

ISBN-13: 9780415391726 / Angielski / Twarda / 2007 / 348 str.

Charles Levenback; Anil K. Sood; Robert L. Coleman

Opis

Much of the most interesting recent work in gynecologic oncology has been on the factors that can be used to gauge the prognosis of the various cancers. This text brings together the most clinically relevant aspects of this research.

Spis treści

Part I. Ovary 1. Clinical predictors of outcome in epithelial ovarian carcinoma 2. Influence of BRCA1 and BRCA2 on survival 3. Cell-cycle and apoptotic markers 4. p53 as a prognostic factor 5.Use of microarray and CGH technologies for predicting outcome 6. Angiogenesis and epithelial ovarian carcinoma 7. Cell-adhesion and matrix-associated proteins in ovarian carcinoma 8. Effect of immune factors on prognosis 9. Predictive factors in germ-cell and stromal tumors Part II. Endometrium 10. Rethinking traditional surgical-pathologic criteria for early stage endometrial cancer: studies of patterns of failure 11. Molecular prognostic and predictive factors in advanced endometrial cancer: implications for therapy 12. Inherited and acquired mismatch repair deficiency 13. Molecular profiling in endometrial cancer: Current research and implications for the future 14. Traditional and molecular predictors of behavior in uterine papillary serous carcinoma and clear cell carcinoma Part III. Cervical 15. Clinical pathologic predictors in patients with cervical cancer 16. Predictors of radiation sensitivity and resistance 17. Molecular prognostic and predictive factors for cervix cancer 18. Virology in the prevention and management of cervical cancer 19. Molecular imaging for cervical cancer 20. Neuroendocrine cancer of cervix: prognostic and predictive factors 21. Predictive values of sentinel lymph nodes

O autorze

Charles F. Levenback, Anil Sood, Karen H Lu, Robert Coleman