Prognostic and Predictive Factors in Breast Cancer

ISBN-13: 9780367386931 / Angielski / Miękka / 2019 / 198 str.

Rosemary A. Walker; Alistair M. Thompson

Opis

Discussing the methodologies involved in measuring and reporting, this book reviews the latest research from international regarding the identification of markers typing breast cancer behavior. It also examines the roles of major predictive markers such as the steroid receptors, p53, and HER-2. The book provides an overview of the prognostic and predictive factors, the role of the pathologist in prognostic factors, determination of occult auxiliary lymph node metastases, and risk factors for recurrence. That focus makes this text extremely useful for oncologists and researchers who want to learn more about best practices in prognoses.

Spis treści

Introduction / Overview. Role of the Pathologist in Assessing Prognostic Factors for Breast Cancer. Determination and Significance of Lymph Node Occult Metastasis in Breast Cancer. Prognostic Value of Proliferation and Apoptosis in Breast Cancer. The Role of Cell-Cell and Cell-Stromal Interactions in Predicting Breast Cancer Behavior. Detection of Minimal Residual Disease in Predicting Outcome in Breast Cancer. Allelic Imbalance / Microsatellite Instability in Breast Cancers and Blood Determining Breast Cancer Behavior. The Use of Steroid Receptors in Predicting Response to Hormonal Therapy. MAP Kinase Family Members and Endocrine Response and Survival in Breast Cancer. p53 and Breast Cancer. Assessment of HER-2 and its Value in Breast Cancer.

O autorze

Rosemary A. Walker, Alastair M. Thompson