Principles of Cancer Biotherapy

ISBN-13: 9789401065016 / Angielski / Miękka / 2011 / 892 str.

R. K. Oldham

Opis

At the time of the first edition of Principles of Cancer Biotherapy, this book represented the first comprehensive textbook on biological therapy. Whereas in 1991, when the second edition was published, there was still some doubt on the part of many oncologists and cancer researchers as to the therapeutic value of these new approaches, it is now generally agreed that biopharmaceuticals are producing major opportunities for new cancer therapies. Cancer biotherapy has truly matured into the fourth modality of cancer treatment. The third edition is now needed as a result of the tremendous progress that has been made in recent years using biologicals in cancer treatment.
The book summarizes an evolving science and a rapidly changing medical practice. As we near the millennium, it now becomes possible to envision a much more diversified system of cancer research and treatment that will afford greater opportunities for patients. Some forms of cancer biotherapy use the strategy of tumour stabilization and control through continued biological therapy, akin to the use of insulin in the treatment of diabetes.
This textbook illustrates new methods of thinking and new strategies for control of cancer. It is always difficult to move from past dogma to future opportunity, but this third edition of Principles of Cancer Biotherapy illustrates why it is so important to the patients, for researchers and clinicians to explore and apply these new opportunities in cancer biotherapy.

Spis treści

Preface. 1. Cancer Biotherapy: General Principles; R.K. Oldham. 2. The Pathogenesis of Cancer Metastasis: Relevance to Biotherapy; R. Radinsky, et al. 3. Developmental Therapeutics and the Design of Clinical Trials; R.K. Oldham. 4. Recombinant Organisms as Sources of Cancer Biotherapeutics; K. Mehta, B.B. Aggarwal. 5. Current Concepts in Immunology; R.K. Oldham. 6. Cancer-Associated Immune Suppression: Therapeutic Alterations with Chemical and Biological Agents; R.K. Oldham. 7. Nonspecific Immunomodulators in Oncology and Hematology; G. Mathe, S. Orbach. 8. Cancer Vaccines: Tumor Epitopes and Gene Therapy; G.C. Fareed, L.E. Spitler. 9. Chemical Inducers of Lymphokines; R.V. Smalley, R.K. Oldham. 10. Lymphokines and Cytokines; W. Lewko, et al. 11. Interferon Therapy in Cancer; R.V. Smalley, et al. 12. Antibody Therapy; R.O. Dillman. 13. Immunotoxins; L.E. Spitler. 14. Drug Immunoconjugates; R.K. Oldham, K.A. Foon. 15. Radiolabeled Monoclonal Antibodies for Localization and Treatment of Metastatic Cancer; H.B. Breitz, et al. 16. Stem Cell/Bone Marrow Transplantation as Biotherapy; R.K. Oldham. 17. Cancer Adoptive Cellular Immunotherapy; J.R. Yannelli. 18. Growth and Maturation Factors in Cancer; R.K. Oldham. 19. G-CSF; G. Morstyn, et al. 20. GM-CSF; A. Jakubowski. 21. Clinical Approaches to Cancer Gene Therapy; K.A. Whartenby, et al. 22. Cancer Biotherapy: 1990s Disease-Related Activity; R.K. Oldham, et al. 23. Speculations for the 1990s; R.K. Oldham. Index.