Pregnancy and Birth After Assisted Reproductive Technologies

ISBN-13: 9783540435310 / Angielski / Miękka / 2002 / 151 str.

Michael Ludwig; R. G. Edwards

Opis

It is a pleasure to see this book in print. It represents work on an immense importance to assisted human conception. Numerous books have presented virtually every aspect of follicular growth, fertilization, male and female sterility and implantation.This is among the rare books dedicated to pr- nancy, birth and infant growth. Since the introduction of IVF, it has been clear that various problems could be associated with pregnancy after assisted human conception. The first clinical IVF pregnancy after the transfer of a 5-day blastocyst turned out to be ectopic, and this subjecthas neverbeen farfrom debates on the safety of assi- ed human conception ever since. Ectopic and heterotopic pregnancies were two factors stressed in early days of wor- wide IVF, and multiple pregnancies emerged as perhaps as an even more serious problem as high degrees of ovarian sti- lation began to be practised in some clinics. These chapters add the experience of the author, working in a large German IVF team, to discussions on these topics in this

Recenzje

From the reviews:

"This book represents work of immense importance to those involved in assisted human conception treatments. ... This book is an excellent reference source on the effects of assisted conception treatment. It will be consulted by clinical and scientific investigators alike and perhaps by general readers. ... the author must be commended on the immense amount of time that must have been spent in attending to the fine detail and collating the data on pregnancy parturition and early development." (Peter Mcfaul, The Obstetrician and Gynaecologist, Vol. 6 (1), 2004)

Spis treści

1 A Follow-up of Pregnancies in Assisted Reproduction: Necessity and Problems.- Why Is It Necessary to Perform a Follow-up of Pregnancies After an ART Procedure?.- Why Do Not All Centres Perform a Follow-up of Pregnancies After an ART Procedure?.- Conclusion.- 2 Incidence of Early Abortions and Ectopic Pregnancies in Assisted Reproduction.- Definitions.- Incidence of Spontaneous Abortions.- IVF.- GIFT.- ICSI.- Frozen/Thawed ET.- Artificial Insemination with Donor Sperm (AID).- Incidence of Ectopic Pregnancies.- Incidence of Heterotopic Pregnancies.- Incidence of Disappearing Gestational Sacs.- Is There a Higher Abortion Risk Following ART?.- 3 Incidence of Chromosomal Abnormalities in Abortions After Assisted Reproduction.- Monosomy.- Trisomy.- Triploidy.- Tetraploidy.- Structural Chromosomal Anomalies.- Mosaics.- Factors that Might Influence the Incidence of Chromosomal Anomalies.- Effect of Ovarian Stimulation.- Effect of ICSI.- Effect of Parental Age.- Conclusion.- 4 Assisted Reproduction and Prenatal Diagnosis.- Invasive Prenatal Diagnosis.- IVF and Prenatal Diagnosis.- ICSI and Prenatal Diagnosis.- Non-invasive Prenatal Diagnosis.- Ultrasound.- Serum Markers for Prenatal Diagnosis.- Conclusion.- 5 Obstetric Outcome of Pregnancies After Assisted Reproduction.- Singletons Conceived by ART Versus Spontaneously Conceived Pregnancies.- Singleton Versus Multiple Pregnancies After IVF or IVF/ICSI.- Multiple Pregnancies After ART Versus Spontaneously Conceived Multiple Pregnancies.- Higher Order Multiple Pregnancies Following ART.- Obstetric Outcome of Pregnancies After Cryopreservation.- Descriptive Studies Without Control Groups.- Controlled Studies.- Conclusion.- 6 Oocyte Donation.- Oocyte Recipients and Donors.- Hormonal Substitution for Oocyte Recipients.- Oocyte Donors.- Follow-up of Oocyte Donors.- Effects of Anonymity and Secrecy.- Obstetric Outcome in Oocyte Donation Pregnancies.- The Impact of Age.- Conclusion.- 7 Congenital Malformations After ART.- Congenital Malformations After IVF.- Congenital Malformations After ICSI.- Congenital Malformations After SUZI.- Congenital Malformations After GIFT or Intrauterine Insemination.- Congenital Malformations After Cryopreservation.- An Increased Risk for Certain Malformations.- Neural Tube Defects.- Alimentary Tract Atresia.- Hypospadias.- Conclusion.- 8 Perinatal Outcome and Follow-up of Children Born from ART.- Descriptive Studies Without Control Groups.- Controlled Studies.- Follow-up of Children From Cryopreserved Embryos.- Conclusion.- 9 Development of Children of Lesbian Mothers After Using Assisted Reproduction Techniques.- Development of Children of Lesbian Mothers in General.- Gender Identity.- Gender Role Behaviour.- Sexual Orientation.- Other Aspects of Personality Development.- Children’s Social Relationships.- Children Conceived Via Donor Insemination by Lesbian Mothers.- Conclusion.- 10 Development of Children and Family Structure After IVF and Gamete Donation.- Children and Their Parents After IVF.- Children and Their Parents After Gamete Donation.- Conclusion.- 11 General Conclusions.- Abbreviation List.- References.

O autorze

Michael Ludwig ist Facharzt für Frauenheilkunde und Geburtshilfe mit dem Schwerpunkt gynäkologische Endokrinologie und Reproduktionsmedizin. Insofern beschäftigt er sich seit vielen Jahren ausschließlich mit den Hormonen der Frau und dem Thema unerfüllter Kinderwunsch. Prof. Ludwig hat mehrere Jahre an der Universitätsfrauenklinik Lübeck im Team von Professor Dr. med. Klaus Diedrich, einem Pionier der Reproduktionsmedizin in Deutschland, gearbeitet. Professor Ludwig leitet heute ein interdisziplinäres Facharztzentrum in Hamburg, das sich vorwiegend mit hormonellen Störungen bei Frau und Mann sowie mit dem unerfüllten Kinderwunsch beschäftigt. Das Team um Professor Ludwig hat in den vergangenen Jahren über 10.000 Kinderwunschpaare beraten und behandelt.