"For pathologists and other physicians looking for a good, comprehensive reference on the molecular pathology of breast lesions, this book offers a good summary of this complex field. Chapters are overall well written, making this a reader friendly resource for pathologists who deal with the interpretation of these molecular findings. This book would be a valuable addition to a departmental and personal library." (Ana G. Yuil-Valdes, Doody's Book Reviews, November, 2015)
Chapter 1 Molecular basis of breast cancer imaging Gopal R. Vijayaraghavan, Srinivasan Vedantham , Ashraf Khan, Andrew Karellas
Chapter 2 Familial Breast Cancer and Genetic Predisposition in Breast Cancer Vighnesh Walavalkar, Ashraf Khan, Dina Kandil
Chapter 3 Modelling the Molecular Pathology of Breast Cancer Initiation Claire Nash, Andrew M. Hanby, Valerie Speirs
Chapter 4 Molecular Pathology of Precancerous Lesions of the Breast Abhik Mukherjee, Ian O. Ellis, Emad A. Rakha
Chapter 5 Breast Cancer Stem Cells: Role in Tumor Initiation, Progression and Targeted Therapy Sanjoy Samanta, Ashraf Khan, Arthur M. Mercurio
Chapter 6 Molecular Pathology of Pre-Invasive Ductal Carcinoma Yuna Gong, Dina Kandil, Ashraf Khan
Chapter 7 Molecular Pathology of Lobular Carcinoma Ali Sakhdari, Lloyd Hutchinson, Ediz Cosar
Chapter 8 Molecular Pathology of Hormone Regulation in Breast Cancer: Hormone Receptor Evaluation and Therapeutic Implications Emad A Rakha
Chapter 9 Molecular Pathology of HER Family of Oncogenes in Breast Cancer: HER-2 Evaluation and Role in Targeted Therapy Lloyd Hutchinson, Ali Sakhdari, Ediz Cosar
Chapter 10 Molecular Classification of Breast Cancer Mohammed Aleskandarany, Ian O. Ellis, Emad A. Rakha
Chapter 11 Triple Negative Breast Cancer: Subtypes with Clinical Implications Dina Kandil, Ashraf Khan
Chapter 12 Molecular-based Diagnostic, Prognostic and Predictive Tests in Breast Cancer Abir A. Muftah, Mohammed Aleskandarany, Ian O. Ellis, Emad A Rakha
Chapter 13 Role of MicroRNAs in Breast Cancer Jennifer M. Clarke, Dina Kandil, Ediz Cosar, Ashraf Khan
Chapter 14 Molecular Pathology of Fibroepithelial Neoplasms of the Breast Michelle Yang, Dina Kandil, Ashraf Khan
Chapter 15 Molecular Features of Mesenchymal Tumors of the
Breast Marjan Mirzabeigi, Ashraf Khan, Dina Kandil
Chapter 16 Molecular Pathology of Breast Cancer Metastasis Mohammed Aleskandarany, Ian O. Ellis, Emad A. Rakha
Chapter 17 The molecular pathology of chemoresistance during the therapeutic response in breast cancer James L Thorne, Andrew M. Hanby, Thomas A. Hughes
Chapter 18 The Molecular Pathology of Male Breast Cancer Rebecca A Millican-Slater, Valerie Speirs, Thomas A. Hughes, Andrew M. Hanby
Chapter 19 Specimens for Molecular Testing in Breast Cancer Ali Sakhdari, Lloyd Hutchinson, Ediz Cosar
Ashraf Khan, MD, FRCPath University of Massachusetts Medical School, Department of Pathology, Worcester, MA, USA
Ian O. Ellis, MD, FRCPath University of Nottingham, Department of Histopathology, Nottingham City Hospital, Nottingham, UK
Andrew M. Hanby, BM, FRCPath St. James University Hospital/University of Leeds, Leeds Institute of Cancer and Pathology, Leeds, West Yorkshire, UK
Ediz F. Cosar, MD UMassMemorial Medical Center, University of Massachusetts Medical School, Department of Pathology, Worcester, MA, USA
Emad Rakha, MD, PhD, FRCPath University of Nottingham, Department of Histopathology, Nottingham City Hospital, Nottingham, UK
Dina Kandil, MD UMassMemorial Medical Center, University of Massachusetts Medical School, Department of Pathology, Worcester, MA, USA
This volume provides a comprehensive review of the molecular mechanisms involved in precancerous lesions and benign and malignant breast tumors. Given the complex molecular pathways in breast cancer biology, the book simplifies these complex mechanisms and highlights the practical issues important for daily practice. Sections are structured to review breast carcinogenesis and the role of familial predisposition and stem cells in initiation and progression of breast cancer. In-depth chapters present morphologic and molecular correlations in precancerous and malignant breast lesions, while outlining highly practical issues that are in practice today in breast pathology, such as evaluation of estrogen, progesterone receptors, and HER-2.
Written by experts in the field, Precision Molecular Pathology of Breast Cancer is a valuable resource that covers the current practice of breast pathology and looks into the future with an emphasis on the molecular basis of breast cancer.