Pre-Clinical and Clinical Methods in Brain Trauma Research

ISBN-13: 9781493985630 / Angielski / Twarda / 2018 / 381 str.

Amit K. Srivastava; Charles S. Cox Jr

Recenzje

"This is a well-organized book of neuromethods in brain trauma intended for trainees in the laboratory ... . The combination of excellent reviews of experimental procedures, clinical information, and detailed protocols will be helpful for graduate students, postdocs and neurosurgery residents. Additionally, clinicians and clinician scientists involved in translational research should find this volume especially useful." (Bruce G. Lyeth, Neurosurgery, Vol. 85 (1), July, 2019)

Spis treści

Series Preface…

Preface…

Table of Contents…

Contributing Authors…

 

1. Traumatic Brain Injury

 Amit K. Srivastava and Charles S. Cox, Jr.

2. Three-Dimensional In Vitro Brain Tissue Models

Min D. Tang-Schomer

3. Modeling Traumatic Brain Injury In Vitro

Daniel E. Bonder, Carolyn E. Keating, Namas Chandra, D. Kacy Cullen, and Bryan J. Pfister

4. Drosophila Model to Study Chronic Traumatic Encephalopathy

Rojahne Azwoir and Liam Chen

5. Controlled Cortical Impact for Modeling Traumatic Brain Injury in Animals

Nicole Osier and C. Edward Dixon

6. Fluid Percussion Model of Traumatic Brain Injury

Rachel K. Rowe, Daniel Griffiths, and Jonathan Lifshitz

7. Development of a Rodent Model of Closed Head Injury: The Maryland Model 

Erik Hayman, Kaspar Kaledjian, Vladimir Gerzanich, and J. Marc Simard

8. Rodent Model of Primary Blast-Induced Traumatic Brain Injury: Guidelines to Blast Methodology

Venkatasivasai Sujith Sajja, Arun Peethambaram, Stephen A. Van Albert, and Joseph B. Long

9. Cognitive and Motor Function Assessments in Rodent Models of Traumatic Brain Injury

Danielle Scott and Kathryn E. Saatman 

10. Pre-Procedural Considerations and Post-Procedural Care for Animal Models with Experimental Traumatic Brain Injury

Mary A. Robinson, Samer M. Jaber, Stacey L. Piotrowski, and Thomas H. Gomez

11. Laser Capture Microdissection of Single Cells, Cell Populations, and Brain Regions Affected by Traumatic Brain Injury

Harris A. Weisz, Deborah R. Boone, Stacy L. Sell, and Helen L. Hellmich

12. Rat Microglia Isolation and Characterization Using Multi-Parametric Panel for Flow Cytometric Analysis

Naama E. Toledano Furman, Karthik S. Prabhakara, Supinder Bedi, Charles S. Cox Jr., and Scott D. Olson

13. The Principles of Experimental Design and the Determination of Sample Size When Using Animal Models of Traumatic Brain Injury  

Michael F.W. Festing

14. Advanced Informatics Methods in Acute Brain Injury Research

Jude P.J. Savarraj, Mary F. McGuire, Ryan Kitagawa, and Huimahn Alex Choi

15. Rapid Detection and Monitoring of Brain Injury Using Sensory Evoked Responses

Jonathan A. N. Fisher and Cristin G. Welle 

16. Advanced Neuroimaging Methods in Traumatic Brain Injury

Jenifer Juranek

17. Dynamic Contrast Enhanced MRI for the Analysis of Blood-Brain Barrier Leakage in Traumatic Brain Injury  

Qiang Shen and Timothy Q. Duong 

18. Assessments for Quantifying Neuromotor Functioning after Repetitive Blast Exposure

Christopher K. Rhea, Nikita A. Kuznetsov, W. Geoff Wright, F. Jay Haran, Scott E. Ross, and Josh L. Duckworth

19. Translingual Neurostimulation (TLNS): Perspective on a Novel Approach to Neurorehabilitation after Brain Injury

Yuri Danilov and Dafna Paltin

20. The Rapid Templating Process for Large Cranial Defects

Jeremy Kwarcinski, Philip Boughton, Andrew Ruys, and James van Gelder

21. Computer-Assisted Approaches to Identify Functional Gene Networks Involved in Traumatic Brain Injury

Anthony San Lucas, John Redell, Pramod Dash, and Yin Liu

22. Clinical Trials for Traumatic Brain Injury: Designs and Challenges

Juan Lu and Mirinda Gormley 

Blurb

This volume explores current viewpoints and knowledge gaps in the field of traumatic brain injury (TBI). The chapters in this book cover topics ranging from development of in vitro and animal TBI models, to diagnostic imaging and disease monitoring in patients. Designing pre-clinical and clinical trials is also discussed. In Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory.

Practical and thorough, Pre-Clinical and Clinical Methods in Brain Trauma Research is a valuable resource for both scientists and clinical researchers interested in learning about important techniques and their applications in the field of TBI.