1. Pragmatism, Precision Oncology, International Partnership for Research and Quality-The New Paradigm for Thyroid Cancer
Ujjal Mallick, Clive Harmer
Section I. Multidisciplinary Approach to Management of Thyroid Cancer
2. The UK Evidence-Based Guidelines for the Management of Thyroid Cancer: Key Recommendations
Maria G. Pavlatou, Sarah J Johnson, and Petros Perros
3. The 2015 American Thyroid Association Evidence-Based Guidelines for Management of Patients with Thyroid Nodules and Differentiated Thyroid Cancer: Key Recommendations
Bryan R. Haugen
4. Thyroid Cancer: One Doctor-Patient Partnership -The Newcastle Butterfly Model
Kate A Farnell, RD Bliss, Ujjal K. Mallick
Section II. The Diagnosis of Thyroid Cancer
5. Molecular Diagnosis of Thyroid Nodules
David N. Poller
6. Ultrasonography in Diagnosis and Management of Thyroid Cancer –Current International Recommendations
Dong Gyu Na, Ji-Hoon Kim, Eun Ju Ha
Section III. Initial Thyroid Surgery
7. The 21st Century Endocrine Surgeon
Nadine R. Caron, Tracy S. Wang, Cord Sturgeon, Orlo H. Clark
8. Management of Cervical Lymph Nodes in Differentiated Thyroid Cancer
Hiro Ishii, Dae S. Kim, John C. Watkinson
9. Advances in Thyroid Surgery
Sara L. Richer, Dipti Kamani, GeorgeW. Randolph
Section IV. Non surgical Management of Differentiated Thyroid Cancer
10. Risk Stratification and Current Management of Low Risk Thyroid Cancer
Sana A. Ghaznavi, R. Michael Tuttle
11 Management of Low risk Papillary Thyroid Carcinomo and Papillary Cancer and Microcarcinoma-the Japanese experience
Yasuhiro Ito and Akira Miyauchi
12 Radioiodine Ablation – Current Status
Furio Pacini and Maria Grazia Castagna -- Sienna
13. Dosimetric Approaches – Current Concepts
Michael Lassmann, Markus Luster, Heribert Hanschield, Wurzberg, Germany
14. External Radiation in Differentiated Thyroid Cancer in the era of IMRT and modern radiation planning techniques
James D. Brierley, Meredith E. Giuliani
Section V. Follow up and Longterm Management of Differentiated Thyroid Cancer
15. Thyroglobulin
Shireen Fatemi, Carole Spencer
16. Management of Post-Operative Hypocalcemia
Claudio Marcocci
17. Radioiodine Refractory Thyroid Cancer
Berdelou A, Leboulleux S, Schlumberger M
Section VI. Medullary Thyroid Carcinoma
18. Medullary Thyroid Cancer :Surgical Management
Anna I. Kaleva ,A R Shaha, and Iain J. Nixon
19. Medullary Thyroid Cancer: Diagnosis and Non Surgical Management
Rossella Elisei, Antonio Matrone
20. Familial Non-Medullary Thyroid Cancer
Joanna Klubo-Gwiezdzinska, Yevgenia Kushchayeva, Sudheer Kumar Gara, Electron Kebebew
Section VII. Thyroid Cancer in Children
21. Pediatric Differentiated Thyroid Carcinoma
Steven G. Waguespack, Jonathan D. Wasserman
Section VIII. Aggressive Thyroid Cancers
22. Anaplastic Thyroid Cancer
Robert C. Smallridge, John Dr. Casler, and Michael E. Menefee
23. Palliative care
Mary Comiskey
Section IX. Future Developments and Directions for Research in Thyroid Cancer.
24. Translational Research and Genomics Driven Trials in Thyroid Cancer
Maria E. Cabanillas, Rebecca E. Schweppe, Ramona Dadu, Gilbert Cote, Thomas C. Beadnell, Marie Claude Hofmann
25. Thyroid Cancer Trials
Allan Hackshaw
26. The Barriers to Uniform Implementation of Clinical Practice Guidelines (CPG) for Thyroid Cancer
Ujjal Mallick, Fabian Pitoia
27. Survivorship: The Role of the Clinical Psychologist and the Clinical Nurse Specialist in Thyroid Cancer Care
Katherine Kendell, Nicola Jane Armstrong
Dr Ujjal Mallick, MBBS MS FRCPE (Hon) FRCP(Hon) FRCR Consultant Clinical Oncologist Formerly Consultant Oncologist and past Chair, Multidisciplinary thyroid cancer team (MDT), Freeman Hospital, Newcastle upon Tyne, UK, a centre of excellence for thyroid cancer. Chief Investigator of the first UK National Thyroid Cancer Trial -Hilo-( NEJM 2012) which helped modify international guidelines and practice and of the on-going second UK trial-IoN. One of the lead authors of the first UK National guideline. The MDT obtained many prestigious national awards including–Best NHS "Hospital Doctor" Oncology Team of the Year” Award 2007, Best Thyroid cancer MDT in NHS Peer Review 2011, first prize in NHS innovations award 2007 and others. He initiated an acclaimed MD clinic involving an expert thyroid cancer patient. Current interests are trials, biomarkers and guideline implementation.
Dr Clive Harmer MB FRCR FRCP. Clinical Oncologist Consultant in Clinical Oncology at St. George’s Healthcare NHS Trust and The Royal Marsden NHS Trust (where he was head of the Thyroid unit) until August 2005. Recognized teacher of the University of London and Honorary Senior Lecturer at the Institute of Cancer Research.
The new edition of this book highlights the recent advances and state-of-the art in surgical and non-surgical management of thyroid cancer. Readers will learn about the latest advances and recommendations in the field, from molecular studies and biomarkers to the changing epidemiology, kinase inhibition in drug discovery and new surgical approaches, such as intra-operative neural monitoring and robotics. The management of differentiated thyroid cancer as well as childhood cancer, survivorship and clinical trial design and findings and how these fit into cancer management are discussed in detail.
This comprehensive volume provides an overview of the current world literature and outlines the practical aspects of management from world leaders in this field and helps clinicians and patients on practical matters. With a selection of authors from around the world it draws on international experience giving a global perspective to the topic. Following on from the success of the first edition, it uses a multidisciplinary, evidence-based approach centered on the patient, discussing guidelines and how these have improved the quality of care and outcomes.
This guide is aimed mainly at thyroidologists of all disciplines, (in training or experts) students, non-specialist clinicians, nursing staff, all the disciplines involved in a multidisciplinary team such as surgeons – Head & Neck or Endocrine and General Surgeons, Oncologists, Endocrinologists, Nuclear Medicine Physicians, Nuclear Medicine Physicists, Radiologists, Pathologists, Specialist Nurses, Geneticists, Clinical Psychologists, Palliative Care Physicians and, of course, patients.