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Post-Transplant Lymphoproliferative Disorders

ISBN-13: 9783030654054 / Angielski / Miękka / 2022 / 330 str.

Post-Transplant Lymphoproliferative Disorders  9783030654054 Springer International Publishing - książkaWidoczna okładka, to zdjęcie poglądowe, a rzeczywista szata graficzna może różnić się od prezentowanej.

Post-Transplant Lymphoproliferative Disorders

ISBN-13: 9783030654054 / Angielski / Miękka / 2022 / 330 str.

cena 401,58
(netto: 382,46 VAT:  5%)

Najniższa cena z 30 dni: 385,52
Termin realizacji zamówienia:
ok. 22 dni roboczych
Dostawa w 2026 r.

Darmowa dostawa!

Post-transplant lymphoproliferative disorders are a group of conditions that straddle the borders between infection and malignancy. They were very rare prior to the mid-1980s but now can be expected to develop in 1-10% of transplant recipients. While some cases are reversible with reduction in immunosuppression, more severe forms are indistinguishable from frank lymphomas.

This book sets out to cover in depth every aspect of these disorders, including both basic science and clinical topics. The epidemiology is reviewed, and careful attention is paid to the role of Epstein-Barr virus in their development. Clinical features are documented and clear guidance is provided on diagnosis, with thorough description of pathologic and imaging findings. Further chapters are devoted to treatment, prognosis, preventive and pre-emptive strategies, and organ-specific considerations.

The state-of-the-art information contained in this book will aid researchers as well as the many different professionals involved in caring for patients with post-transplant lymphoproliferative disorders. The comprehensive and detailed coverage will appeal to those who already have some expertise in the field, yet the book will also serve as an invaluable resource for beginners in transplantation.

Kategorie:
Nauka, Medycyna
Kategorie BISAC:
Medical > Surgery - Transplant
Medical > Oncology - General
Medical > Nefrologia
Wydawca:
Springer International Publishing
Język:
Angielski
ISBN-13:
9783030654054
Rok wydania:
2022
Ilość stron:
330
Waga:
0.46 kg
Wymiary:
23.39 x 15.6 x 1.75
Oprawa:
Miękka
Wolumenów:
01
Dodatkowe informacje:
Wydanie ilustrowane

Introduction and History.- Definitions and Pathology of PTLD.- EBV Biology in the Pathogenesis of PTLD.- Host genetic mutations and expression analyses in PTLD.- Immune responses to EBV in the immunocompromised host.- Technical aspects of Epstein-Barr viral load assays.- Epidemiology of PTLD after SOT.- Clinical Features and Diagnostic Considerations.- Prognostic Factors.- Management of PTLD.- Prevention of Epstein - Barr virus Infection and Post-Transplant Lymphoproliferative Disorders Following Transplantation.- Epidemiology and Prognosis of PTLD after HSCT.- Clinical Presentations and Features of PTLD after Hematopoietic Stem Cell Transplantation.- Management of PTLD after HSCT.- Preventative and preemptive strategies for EBV infection and PTLD after hematopoietic stem cell transplantation.- Organ Specific issues of PTLD – Kidney.- Liver.- Post-transplantation Lymphoproliferative Disorder in Intestinal Transplant Recipients.- PTLD After Heart Transplantation.- Lung Transplantation.- Research Priorities and Future Directions.

Vikas R. Dharnidharka
Division of Pediatric Nephrology Hypertension and Pheresis
Washington University School of Medicine
St. Louis, MO
USA
 
Michael Green
Departments of Pediatrics and Surgery
University of Pittsburgh School of Medicine
UPMC Children's Hospital of Pittsburgh
Pittsburgh, PA
USA
 
Steven A. Webber
Department of Pediatrics
Vanderbilt University School of Medicine
Nashville, TN
USA
 
Ralf Ulrich Trappe
Department of Hematology and Oncology
DIAKO Ev. Diakonie-Krankenhaus Bremen
Bremen, Germany

This disorder transcends multiple disciplines and demands a team approach to improve knowledge and treatment. The highly experienced internationally recognized authors have updated every section and added many new chapters, including some on genetic abnormalities in virus and host seen in PTLDs. In this successor edition, there is a completely new section on PTLDs after hematopoietic stem cell transplantation. The newest PTLD classifications and current treatment paradigms that reflect recently conducted international trials are fully incorporated. As technologies have advanced, this book provided state-of-the-art new diagnostic and prognostic information.

Post-Transplant Lymphoproliferative Disorders 2nd Edition is designed to be a valuable reference for oncologists and all transplant professionals, such as surgeons, nephrologists, cardiologists, hepatologists/gastroenterologists, pulmonologists, infectious disease specialists, pathologists, as well as interns and residents in training in these specialists. It provides these professionals with comprehensive and up-to-date information that guides their management of transplant patients before and after transplant, with and without PTLD. 



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