Positron Emission Tomography: A Critical Assessment of Recent Trends

ISBN-13: 9789401060974 / Angielski / Miękka / 2012 / 482 str.

Balazs Gulyas;Hans W. Muller-Gartner

Opis

A critical summary of the state of the art of PET technology and related disciplines (camera physics, radiochemistry, radiopharmacology, computerised brain atlases and databases, etc.), plus a survey of the most recent developments in the clinical and neuroscience applications of PET.
The chapters systematically guide the reader from the basics of the technique - including new camera designs, new drugs, and new statistical and image processing approaches - through its most important clinical applications - in neurology, psychiatry and oncology - to the most sophisticated neuroscience applications, including research into human sensory and motor systems, the functional organisation of imagery, volition, attention and consciousness in the human brain.

Spis treści

Preface. Part One: How to Establish and Run a PET Center? 1. Planning a Proposal for a PET Centre; A. Holley. 2. The Use and Registration of PET Radiopharmaceuticals. European and World Trends; G.-J. Meyer. 3. FDG Distribution - A New Market Trend; S.R. Lindbäck. 4. Status of Clinical PET in the USA and the Role and Activities of the Institute for Clinical PET; P.D. Shreve. Part Two: PET: Novel Methodological Approaches. 5. Recent Trends in PET Camera Designs; D.L. Bailey. 6. Strategies for Radioligand Development: Peptides for Tumor Targeting; G. Stöcklin, H.-J. Wester. 7. Development of PET Radioligands for the Quantitation of Serotonin Receptors in the Human Brain; C. Halldin, et al. 8. The Renin- Angiotensin System; Z. Szabó. 9. Membrane Transporters; Z. Szabó. 10. A Deformable High Resolution Anatomic Reference for PET Activation Studies; A.W. Toga. 11. Registration: A Powerful Tool to Combine Information Provided by Different Imaging Modalities; M. Emri, et al. 12. Quantification of FDG Uptake Using Kinetic Models; L. Balkay, et al. 13. Cavinton Affects the Kinetic Constants of FDG Accumulation: An Application of Registration and Kinetic Modelling; L. Trón, et al. 14. Whole Body Scanning; M. Dahlbom. Part Three: PET in Oncology. 15. Positron Emission Tomography in Oncology. In Vivo Measurements of Protein Synthesis in Tumors; A.M.J. Paans, et al. 16. Diagnosis Differential Diagnosis, and Follow-Up of Tumors by Means of FDG PET; O.Ésik, et al. 17. Clinical Application of Whole-Body [18]-FDG-PET in Malignant Melanoma; H.C. Steinert. 18. Evaluation of Metastatic Lymph Nodes by Means of FDG PET; J. Lövey, et al. 19. Diagnosis, Differential Diagnosis, and Follow-Up of Intracranial Tumors with PET; K. Borbély. Part Four: PET in Neurology and Psychiatry. 20. PET Studies in Neuropharmacology. Novel Approaches; D.J. Brooks. 21. PET Studies of the Dopamine Hypotheses in Schizophrenia; A.-L. Nordström. 22. PET and Epilepsy in Adults; I. Savic. 23. Mapping Cerebral Responses to Volatile Anesthetics in Humans; F. Gyulai. 24. The Effect of a Single-Dose Intravenous Vinpocetine on Chronic Stroke Patients. A PET Study; B. Gulyás, et al. 25. Coupling Between Cerebral Blood Flow and Metabolism in the Primate: Methodological and Pharmacological Issues; P. Schumann, E.T. MacKenzie. Part Five: PET in Neuroscience Research. 26. BrainMap™: Electronic Integration of Mind and Brain; P.T. Fox, J.L. Lancaster. 27. Designing Activation Experiments; K.J. Friston, et al. 28. The Human Motor System: Principles Versus Plasticity; R.J. Seitz, et al. 29. Area Borders in Human Visual Cortex: An Integrated PET and Cytoarchitectonic Study; B. Gulyás, et al. 30. Activation of the Visual Ventral Stream in Humans: An fMRI Study; N.J. Shah, et al. 31. PET and fMRI Studies of Cerebellar Function in Sensation, Perception, and Cognition; L.M. Parsons, P.T. Fox. 32.