Polymer-Drug Conjugates: Linker Chemistry, Protocols and Applications

ISBN-13: 9780323916639 / Miękka / 2023

Madan, Jitender

Spis treści

1. Drug Delivery: The conceptual perspectives and therapeutic applications
2. Rational design of linkers in polymer drug conjugates
3. Exploration of polymers in drug delivery: The structural and functional considerations
4. Chemistry of conjugation in drug delivery: The prospects of biodegradable and non-biodegradable bonds
5. Polymer-drug conjugation using ester and orthoester bond: Mechanism, protocols and applications
6. Polymer-drug linking through amide bonds: The chemistry and applications in drug delivery
7. Drug-Polymer conjugate tailoring by disulfide linkage and its exploration in drug distribution
8. Thioether linkage Chemistry: Perspectives and prospects in therapeutic designing
9. Drug targeting to cancer cells through stimuli responsive imine bonds: Fascinating aspects of site specificity
10. Carbamate-drug conjugates in drug delivery: Structural and mechanistic considerations
11. Bonding through phosphodiester moiety: Its implications in pharmaceutical modifications
12. Enzymatically degradable linkers
13. Dendrimer-Drug conjugates
14. Antibody-Drug conjugates
15. Polymer-Drug Conjugates in Clinical Trials: Challenges, Opportunities and Future prospects